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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CASKIN1 All Species: 19.09
Human Site: S1377 Identified Species: 38.18
UniProt: Q8WXD9 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WXD9 NP_065815.1 1431 149814 S1377 R Q K L E E T S A C L A A A L
Chimpanzee Pan troglodytes XP_523265 1472 154891 P1435 P A P P T H A P C P A P R S D
Rhesus Macaque Macaca mulatta XP_001084114 1449 151732 S1395 R Q K L E E T S A C L A A A L
Dog Lupus familis XP_853631 1347 141422 S1310 T R P S L S A S T A K P P P S
Cat Felis silvestris
Mouse Mus musculus Q6P9K8 1431 150477 S1376 R Q K L E E T S A C L A A A L
Rat Rattus norvegicus Q8VHK2 1430 150329 S1375 R Q K L E E T S A C L A A A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507411 400 42074 R363 P E Q R P G P R P G P E P S L
Chicken Gallus gallus XP_414857 1448 153132 S1394 Q Q K L E E T S A S L A A A L
Frog Xenopus laevis Q6DD51 1205 130900 Q1168 L Q N T E E L Q D T R G K S C
Zebra Danio Brachydanio rerio XP_692620 1293 139986 Q1256 V V E R K L A Q D D P A S R G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392417 814 88839 S777 S L D A S S G S L S S V S L S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795586 2231 243152 P2182 V L K L Q T S P S L P S P P L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.6 95 85.5 N.A. 90.2 90.2 N.A. 20.3 72.1 38.2 43.4 N.A. N.A. 22.5 N.A. 26.6
Protein Similarity: 100 88.4 96.1 87.4 N.A. 93 93.1 N.A. 24.1 79.2 51.7 56.8 N.A. N.A. 35 N.A. 39.2
P-Site Identity: 100 0 100 6.6 N.A. 100 100 N.A. 6.6 86.6 20 6.6 N.A. N.A. 6.6 N.A. 20
P-Site Similarity: 100 6.6 100 13.3 N.A. 100 100 N.A. 26.6 93.3 26.6 26.6 N.A. N.A. 13.3 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 9 0 0 25 0 42 9 9 50 42 42 0 % A
% Cys: 0 0 0 0 0 0 0 0 9 34 0 0 0 0 9 % C
% Asp: 0 0 9 0 0 0 0 0 17 9 0 0 0 0 9 % D
% Glu: 0 9 9 0 50 50 0 0 0 0 0 9 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 9 9 0 0 9 0 9 0 0 9 % G
% His: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 50 0 9 0 0 0 0 0 9 0 9 0 0 % K
% Leu: 9 17 0 50 9 9 9 0 9 9 42 0 0 9 59 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 17 0 17 9 9 0 9 17 9 9 25 17 25 17 0 % P
% Gln: 9 50 9 0 9 0 0 17 0 0 0 0 0 0 0 % Q
% Arg: 34 9 0 17 0 0 0 9 0 0 9 0 9 9 0 % R
% Ser: 9 0 0 9 9 17 9 59 9 17 9 9 17 25 17 % S
% Thr: 9 0 0 9 9 9 42 0 9 9 0 0 0 0 0 % T
% Val: 17 9 0 0 0 0 0 0 0 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _