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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CASKIN1 All Species: 23.94
Human Site: S822 Identified Species: 47.88
UniProt: Q8WXD9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WXD9 NP_065815.1 1431 149814 S822 E R P M S P R S L P Q S P T H
Chimpanzee Pan troglodytes XP_523265 1472 154891 S963 E R P M S P R S L P Q S P T H
Rhesus Macaque Macaca mulatta XP_001084114 1449 151732 S843 E R P M S P R S L P Q S P T H
Dog Lupus familis XP_853631 1347 141422 S803 E R P M S P R S L P Q S P T H
Cat Felis silvestris
Mouse Mus musculus Q6P9K8 1431 150477 P826 P M S P R S L P Q S P T H R G
Rat Rattus norvegicus Q8VHK2 1430 150329 S823 D R P M S P R S L P Q S P T H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507411 400 42074
Chicken Gallus gallus XP_414857 1448 153132 S820 E R P A S P R S L P Q S P T H
Frog Xenopus laevis Q6DD51 1205 130900 V696 S S Y P V L P V H L Q G V D L
Zebra Danio Brachydanio rerio XP_692620 1293 139986 E779 S D S S P S K E Q Y A I R E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392417 814 88839 D305 P I P V Q G N D S L G S P Y E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795586 2231 243152 T1002 P E K L R T A T I G R K K S M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.6 95 85.5 N.A. 90.2 90.2 N.A. 20.3 72.1 38.2 43.4 N.A. N.A. 22.5 N.A. 26.6
Protein Similarity: 100 88.4 96.1 87.4 N.A. 93 93.1 N.A. 24.1 79.2 51.7 56.8 N.A. N.A. 35 N.A. 39.2
P-Site Identity: 100 100 100 100 N.A. 0 93.3 N.A. 0 93.3 6.6 0 N.A. N.A. 20 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 6.6 100 N.A. 0 93.3 6.6 6.6 N.A. N.A. 26.6 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 0 9 0 0 0 9 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 9 0 0 0 0 0 9 0 0 0 0 0 9 0 % D
% Glu: 42 9 0 0 0 0 0 9 0 0 0 0 0 9 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 9 0 0 0 9 9 9 0 0 9 % G
% His: 0 0 0 0 0 0 0 0 9 0 0 0 9 0 50 % H
% Ile: 0 9 0 0 0 0 0 0 9 0 0 9 0 0 0 % I
% Lys: 0 0 9 0 0 0 9 0 0 0 0 9 9 0 0 % K
% Leu: 0 0 0 9 0 9 9 0 50 17 0 0 0 0 9 % L
% Met: 0 9 0 42 0 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % N
% Pro: 25 0 59 17 9 50 9 9 0 50 9 0 59 0 0 % P
% Gln: 0 0 0 0 9 0 0 0 17 0 59 0 0 0 0 % Q
% Arg: 0 50 0 0 17 0 50 0 0 0 9 0 9 9 0 % R
% Ser: 17 9 17 9 50 17 0 50 9 9 0 59 0 9 9 % S
% Thr: 0 0 0 0 0 9 0 9 0 0 0 9 0 50 0 % T
% Val: 0 0 0 9 9 0 0 9 0 0 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 0 0 0 0 9 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _