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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CASKIN1 All Species: 20.91
Human Site: T1123 Identified Species: 41.82
UniProt: Q8WXD9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WXD9 NP_065815.1 1431 149814 T1123 A K V E A S A T L K R R I R A
Chimpanzee Pan troglodytes XP_523265 1472 154891 S1225 A R R G P G E S A D P G P F V
Rhesus Macaque Macaca mulatta XP_001084114 1449 151732 T1144 A R V E A S A T L K R R I R A
Dog Lupus familis XP_853631 1347 141422 L1100 A S A E G P S L A R V E A S A
Cat Felis silvestris
Mouse Mus musculus Q6P9K8 1431 150477 T1125 A R V E A S A T L K R R I R A
Rat Rattus norvegicus Q8VHK2 1430 150329 T1124 A R V E A S A T L K R R I R A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507411 400 42074 A153 P T A L N V R A G A V I T V L
Chicken Gallus gallus XP_414857 1448 153132 T1157 A K V E A S A T L K R R I R A
Frog Xenopus laevis Q6DD51 1205 130900 A958 Q E S Q L Q S A E A Q R H L E
Zebra Danio Brachydanio rerio XP_692620 1293 139986 P1046 H A D Q N V S P L R H Q Q G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392417 814 88839 I567 R S G A R S H I D L E Q L Q K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795586 2231 243152 T1595 A E I D E D L T T D V S S S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.6 95 85.5 N.A. 90.2 90.2 N.A. 20.3 72.1 38.2 43.4 N.A. N.A. 22.5 N.A. 26.6
Protein Similarity: 100 88.4 96.1 87.4 N.A. 93 93.1 N.A. 24.1 79.2 51.7 56.8 N.A. N.A. 35 N.A. 39.2
P-Site Identity: 100 6.6 93.3 20 N.A. 93.3 93.3 N.A. 0 100 6.6 6.6 N.A. N.A. 6.6 N.A. 13.3
P-Site Similarity: 100 20 100 33.3 N.A. 100 100 N.A. 0 100 33.3 40 N.A. N.A. 26.6 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 67 9 17 9 42 0 42 17 17 17 0 0 9 0 50 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 9 0 9 0 0 9 17 0 0 0 0 0 % D
% Glu: 0 17 0 50 9 0 9 0 9 0 9 9 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % F
% Gly: 0 0 9 9 9 9 0 0 9 0 0 9 0 9 0 % G
% His: 9 0 0 0 0 0 9 0 0 0 9 0 9 0 0 % H
% Ile: 0 0 9 0 0 0 0 9 0 0 0 9 42 0 0 % I
% Lys: 0 17 0 0 0 0 0 0 0 42 0 0 0 0 9 % K
% Leu: 0 0 0 9 9 0 9 9 50 9 0 0 9 9 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 17 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 9 0 0 0 9 9 0 9 0 0 9 0 9 0 0 % P
% Gln: 9 0 0 17 0 9 0 0 0 0 9 17 9 9 0 % Q
% Arg: 9 34 9 0 9 0 9 0 0 17 42 50 0 42 0 % R
% Ser: 0 17 9 0 0 50 25 9 0 0 0 9 9 17 17 % S
% Thr: 0 9 0 0 0 0 0 50 9 0 0 0 9 0 0 % T
% Val: 0 0 42 0 0 17 0 0 0 0 25 0 0 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _