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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CASKIN1 All Species: 19.09
Human Site: T814 Identified Species: 38.18
UniProt: Q8WXD9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WXD9 NP_065815.1 1431 149814 T814 T P Q L L P P T E R P M S P R
Chimpanzee Pan troglodytes XP_523265 1472 154891 T955 T P Q L L P P T E R P M S P R
Rhesus Macaque Macaca mulatta XP_001084114 1449 151732 T835 T P Q L L P P T E R P M S P R
Dog Lupus familis XP_853631 1347 141422 T795 T P Q L L P P T E R P M S P R
Cat Felis silvestris
Mouse Mus musculus Q6P9K8 1431 150477 R818 Q L L P P T D R P M S P R S L
Rat Rattus norvegicus Q8VHK2 1430 150329 T815 T P Q L L P P T D R P M S P R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507411 400 42074
Chicken Gallus gallus XP_414857 1448 153132 G812 T P Q L L P P G E R P A S P R
Frog Xenopus laevis Q6DD51 1205 130900 A688 S G H S Q E S A S S Y P V L P
Zebra Danio Brachydanio rerio XP_692620 1293 139986 S771 R S Q E S L G S S D S S P S K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392417 814 88839 P297 D A D S E N L P P I P V Q G N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795586 2231 243152 D994 S M I T T V P D P E K L R T A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.6 95 85.5 N.A. 90.2 90.2 N.A. 20.3 72.1 38.2 43.4 N.A. N.A. 22.5 N.A. 26.6
Protein Similarity: 100 88.4 96.1 87.4 N.A. 93 93.1 N.A. 24.1 79.2 51.7 56.8 N.A. N.A. 35 N.A. 39.2
P-Site Identity: 100 100 100 100 N.A. 0 93.3 N.A. 0 86.6 0 6.6 N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 0 100 N.A. 0 86.6 6.6 20 N.A. N.A. 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 0 0 9 0 0 0 9 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 9 0 0 0 9 9 9 9 0 0 0 0 0 % D
% Glu: 0 0 0 9 9 9 0 0 42 9 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 0 0 0 0 9 9 0 0 0 0 0 9 0 % G
% His: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 0 0 0 0 0 0 9 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 9 % K
% Leu: 0 9 9 50 50 9 9 0 0 0 0 9 0 9 9 % L
% Met: 0 9 0 0 0 0 0 0 0 9 0 42 0 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 9 % N
% Pro: 0 50 0 9 9 50 59 9 25 0 59 17 9 50 9 % P
% Gln: 9 0 59 0 9 0 0 0 0 0 0 0 9 0 0 % Q
% Arg: 9 0 0 0 0 0 0 9 0 50 0 0 17 0 50 % R
% Ser: 17 9 0 17 9 0 9 9 17 9 17 9 50 17 0 % S
% Thr: 50 0 0 9 9 9 0 42 0 0 0 0 0 9 0 % T
% Val: 0 0 0 0 0 9 0 0 0 0 0 9 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _