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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASKIN1
All Species:
22.42
Human Site:
Y457
Identified Species:
44.85
UniProt:
Q8WXD9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WXD9
NP_065815.1
1431
149814
Y457
V
A
H
A
G
Q
V
Y
G
E
Q
P
P
K
K
Chimpanzee
Pan troglodytes
XP_523265
1472
154891
Y598
V
A
H
A
G
Q
V
Y
G
E
Q
P
P
K
K
Rhesus Macaque
Macaca mulatta
XP_001084114
1449
151732
Y478
V
A
H
T
G
Q
I
Y
G
E
Q
P
P
K
K
Dog
Lupus familis
XP_853631
1347
141422
Y432
A
A
H
A
G
Q
V
Y
G
E
Q
P
P
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q6P9K8
1431
150477
Y457
A
A
H
A
G
Q
V
Y
G
E
Q
P
P
K
K
Rat
Rattus norvegicus
Q8VHK2
1430
150329
Y457
A
A
H
A
G
Q
V
Y
G
E
Q
P
P
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507411
400
42074
Chicken
Gallus gallus
XP_414857
1448
153132
P464
S
P
Y
A
P
Q
P
P
A
E
Q
Q
L
K
K
Frog
Xenopus laevis
Q6DD51
1205
130900
E343
F
F
P
P
S
I
V
E
V
I
S
K
R
L
G
Zebra Danio
Brachydanio rerio
XP_692620
1293
139986
N424
W
V
L
R
T
S
L
N
G
D
R
N
S
I
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392417
814
88839
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795586
2231
243152
S613
R
P
H
S
D
G
I
S
D
F
H
V
D
A
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.6
95
85.5
N.A.
90.2
90.2
N.A.
20.3
72.1
38.2
43.4
N.A.
N.A.
22.5
N.A.
26.6
Protein Similarity:
100
88.4
96.1
87.4
N.A.
93
93.1
N.A.
24.1
79.2
51.7
56.8
N.A.
N.A.
35
N.A.
39.2
P-Site Identity:
100
100
86.6
86.6
N.A.
93.3
93.3
N.A.
0
40
6.6
6.6
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
0
46.6
6.6
26.6
N.A.
N.A.
0
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
50
0
50
0
0
0
0
9
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
0
0
9
9
0
0
9
0
0
% D
% Glu:
0
0
0
0
0
0
0
9
0
59
0
0
0
0
0
% E
% Phe:
9
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
0
0
0
50
9
0
0
59
0
0
0
0
0
17
% G
% His:
0
0
59
0
0
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
17
0
0
9
0
0
0
9
9
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
9
0
50
59
% K
% Leu:
0
0
9
0
0
0
9
0
0
0
0
0
9
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% N
% Pro:
0
17
9
9
9
0
9
9
0
0
0
50
50
0
0
% P
% Gln:
0
0
0
0
0
59
0
0
0
0
59
9
0
0
0
% Q
% Arg:
9
0
0
9
0
0
0
0
0
0
9
0
9
9
0
% R
% Ser:
9
0
0
9
9
9
0
9
0
0
9
0
9
0
0
% S
% Thr:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% T
% Val:
25
9
0
0
0
0
50
0
9
0
0
9
0
0
0
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _