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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASKIN2
All Species:
20.61
Human Site:
S406
Identified Species:
41.21
UniProt:
Q8WXE0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WXE0
NP_001136115.1
1202
126711
S406
G
D
R
N
S
V
G
S
E
G
S
V
G
S
I
Chimpanzee
Pan troglodytes
XP_001137464
1108
116473
D365
L
H
P
P
S
L
A
D
N
L
S
H
R
P
L
Rhesus Macaque
Macaca mulatta
XP_001097098
1204
126819
S406
G
D
R
N
S
V
G
S
E
G
S
V
G
S
I
Dog
Lupus familis
XP_540433
1202
126911
S406
G
D
R
N
S
V
G
S
E
G
S
V
G
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHK1
1201
126791
S406
G
D
R
N
S
V
G
S
E
G
S
V
G
S
I
Rat
Rattus norvegicus
Q8VHK2
1430
150329
H406
S
T
G
G
H
A
L
H
A
G
A
E
G
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507411
400
42074
Chicken
Gallus gallus
XP_420128
1488
159878
S423
G
D
R
N
S
V
G
S
E
G
S
I
G
S
I
Frog
Xenopus laevis
Q6DD51
1205
130900
A406
S
E
S
S
V
R
S
A
G
S
G
Q
S
C
E
Zebra Danio
Brachydanio rerio
A5PMU4
1280
141475
T452
N
P
Y
E
S
V
A
T
A
V
T
R
K
P
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392417
814
88839
A89
G
S
S
P
L
H
L
A
A
W
A
G
D
A
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795586
2231
243152
T411
T
W
S
N
R
E
S
T
E
H
S
T
P
M
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.9
98
92
N.A.
89.7
43.5
N.A.
27.2
51.2
48.8
21
N.A.
N.A.
25.6
N.A.
25.8
Protein Similarity:
100
91.9
98.1
94
N.A.
91.7
56.2
N.A.
30.1
60.9
60.1
36
N.A.
N.A.
38
N.A.
35.8
P-Site Identity:
100
13.3
100
100
N.A.
100
13.3
N.A.
0
93.3
0
13.3
N.A.
N.A.
6.6
N.A.
20
P-Site Similarity:
100
26.6
100
100
N.A.
100
20
N.A.
0
100
20
26.6
N.A.
N.A.
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
17
17
25
0
17
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% C
% Asp:
0
42
0
0
0
0
0
9
0
0
0
0
9
0
0
% D
% Glu:
0
9
0
9
0
9
0
0
50
0
0
9
0
0
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
50
0
9
9
0
0
42
0
9
50
9
9
50
0
0
% G
% His:
0
9
0
0
9
9
0
9
0
9
0
9
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
42
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% K
% Leu:
9
0
0
0
9
9
17
0
0
9
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
9
0
0
50
0
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
0
9
9
17
0
0
0
0
0
0
0
0
9
17
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% Q
% Arg:
0
0
42
0
9
9
0
0
0
0
0
9
9
0
9
% R
% Ser:
17
9
25
9
59
0
17
42
0
9
59
0
9
42
0
% S
% Thr:
9
9
0
0
0
0
0
17
0
0
9
9
0
0
0
% T
% Val:
0
0
0
0
9
50
0
0
0
9
0
34
0
9
0
% V
% Trp:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _