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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASKIN2
All Species:
8.79
Human Site:
S725
Identified Species:
17.58
UniProt:
Q8WXE0
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WXE0
NP_001136115.1
1202
126711
S725
Q
P
S
G
G
D
P
S
P
P
Q
E
R
N
L
Chimpanzee
Pan troglodytes
XP_001137464
1108
116473
P633
S
G
G
D
P
S
P
P
Q
E
R
N
L
P
E
Rhesus Macaque
Macaca mulatta
XP_001097098
1204
126819
P727
S
S
G
D
P
S
N
P
Q
E
R
N
L
P
E
Dog
Lupus familis
XP_540433
1202
126911
S726
Q
P
S
G
G
D
S
S
T
P
Q
E
R
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHK1
1201
126791
S724
Q
P
S
V
G
D
P
S
A
P
Q
E
R
N
L
Rat
Rattus norvegicus
Q8VHK2
1430
150329
P807
P
A
T
A
K
V
K
P
T
P
Q
L
L
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507411
400
42074
Chicken
Gallus gallus
XP_420128
1488
159878
G832
L
T
A
Q
K
G
A
G
P
V
G
T
L
M
V
Frog
Xenopus laevis
Q6DD51
1205
130900
L698
Y
P
V
L
P
V
H
L
Q
G
V
D
L
N
L
Zebra Danio
Brachydanio rerio
A5PMU4
1280
141475
S779
G
Q
S
S
P
G
K
S
S
P
S
R
L
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392417
814
88839
N357
M
S
F
E
D
E
Q
N
G
G
P
V
N
G
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795586
2231
243152
A1412
R
P
V
V
G
T
Q
A
I
E
Q
A
Q
N
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.9
98
92
N.A.
89.7
43.5
N.A.
27.2
51.2
48.8
21
N.A.
N.A.
25.6
N.A.
25.8
Protein Similarity:
100
91.9
98.1
94
N.A.
91.7
56.2
N.A.
30.1
60.9
60.1
36
N.A.
N.A.
38
N.A.
35.8
P-Site Identity:
100
6.6
0
86.6
N.A.
86.6
13.3
N.A.
0
6.6
20
20
N.A.
N.A.
0
N.A.
26.6
P-Site Similarity:
100
13.3
6.6
86.6
N.A.
86.6
20
N.A.
0
20
26.6
20
N.A.
N.A.
20
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
9
0
0
9
9
9
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
17
9
25
0
0
0
0
0
9
0
0
0
% D
% Glu:
0
0
0
9
0
9
0
0
0
25
0
25
0
9
17
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
9
17
17
34
17
0
9
9
17
9
0
0
9
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% I
% Lys:
0
0
0
0
17
0
17
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
0
9
0
0
0
9
0
0
0
9
50
0
34
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
0
0
9
9
0
0
0
17
9
42
0
% N
% Pro:
9
42
0
0
34
0
25
25
17
42
9
0
0
25
9
% P
% Gln:
25
9
0
9
0
0
17
0
25
0
42
0
9
0
0
% Q
% Arg:
9
0
0
0
0
0
0
0
0
0
17
9
25
0
9
% R
% Ser:
17
17
34
9
0
17
9
34
9
0
9
0
0
0
0
% S
% Thr:
0
9
9
0
0
9
0
0
17
0
0
9
0
0
0
% T
% Val:
0
0
17
17
0
17
0
0
0
9
9
9
0
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _