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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CASKIN2 All Species: 15.15
Human Site: S914 Identified Species: 30.3
UniProt: Q8WXE0 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WXE0 NP_001136115.1 1202 126711 S914 L S E P A G P S E P P G P P A
Chimpanzee Pan troglodytes XP_001137464 1108 116473 S820 L S E P A G P S E P P G P P A
Rhesus Macaque Macaca mulatta XP_001097098 1204 126819 S916 L S E P A G P S E P T G P P A
Dog Lupus familis XP_540433 1202 126911 S913 L S E P T G P S E P P S P P V
Cat Felis silvestris
Mouse Mus musculus Q8VHK1 1201 126791 P909 T L S E P T G P S E S P G P S
Rat Rattus norvegicus Q8VHK2 1430 150329 T1077 P V T G L L A T A R R G P G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507411 400 42074 A128 I K Q M L R E A S G I L Q V R
Chicken Gallus gallus XP_420128 1488 159878 S1166 K P E V S S S S Q N S S S E C
Frog Xenopus laevis Q6DD51 1205 130900 L885 V S E S A A G L G G R L S L P
Zebra Danio Brachydanio rerio A5PMU4 1280 141475 H982 L R E P T G N H T P P Q L S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392417 814 88839 L542 H L Q T Q M S L S A D C T L G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795586 2231 243152 Y1678 N Q S P V S K Y A P F S F E T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.9 98 92 N.A. 89.7 43.5 N.A. 27.2 51.2 48.8 21 N.A. N.A. 25.6 N.A. 25.8
Protein Similarity: 100 91.9 98.1 94 N.A. 91.7 56.2 N.A. 30.1 60.9 60.1 36 N.A. N.A. 38 N.A. 35.8
P-Site Identity: 100 100 93.3 80 N.A. 6.6 13.3 N.A. 0 13.3 20 40 N.A. N.A. 0 N.A. 13.3
P-Site Similarity: 100 100 93.3 80 N.A. 13.3 20 N.A. 20 26.6 26.6 40 N.A. N.A. 6.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 34 9 9 9 17 9 0 0 0 0 25 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 9 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % D
% Glu: 0 0 59 9 0 0 9 0 34 9 0 0 0 17 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 9 0 9 0 0 % F
% Gly: 0 0 0 9 0 42 17 0 9 17 0 34 9 9 9 % G
% His: 9 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % I
% Lys: 9 9 0 0 0 0 9 0 0 0 0 0 0 0 0 % K
% Leu: 42 17 0 0 17 9 0 17 0 0 0 17 9 17 0 % L
% Met: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 0 0 0 0 9 0 0 9 0 0 0 0 0 % N
% Pro: 9 9 0 50 9 0 34 9 0 50 34 9 42 42 17 % P
% Gln: 0 9 17 0 9 0 0 0 9 0 0 9 9 0 0 % Q
% Arg: 0 9 0 0 0 9 0 0 0 9 17 0 0 0 9 % R
% Ser: 0 42 17 9 9 17 17 42 25 0 17 25 17 9 9 % S
% Thr: 9 0 9 9 17 9 0 9 9 0 9 0 9 0 9 % T
% Val: 9 9 0 9 9 0 0 0 0 0 0 0 0 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _