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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CASKIN2 All Species: 31.82
Human Site: T252 Identified Species: 63.64
UniProt: Q8WXE0 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WXE0 NP_001136115.1 1202 126711 T252 V D V N I R N T Y N Q T A L D
Chimpanzee Pan troglodytes XP_001137464 1108 116473 T216 V R A G D V I T V L E Q H P D
Rhesus Macaque Macaca mulatta XP_001097098 1204 126819 T252 V D V N I R N T Y N Q T A L D
Dog Lupus familis XP_540433 1202 126911 T252 V D V N I R N T Y N Q T A L D
Cat Felis silvestris
Mouse Mus musculus Q8VHK1 1201 126791 T252 V D V N I R N T Y N Q T A L D
Rat Rattus norvegicus Q8VHK2 1430 150329 T252 I N A Q V R N T Y S Q T A L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507411 400 42074
Chicken Gallus gallus XP_420128 1488 159878 T252 V D V N I R N T Y N Q T A L D
Frog Xenopus laevis Q6DD51 1205 130900 T252 V D V N I R N T Y N Q T A L D
Zebra Danio Brachydanio rerio A5PMU4 1280 141475 C256 I D A N I R D C Q G R T A L D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392417 814 88839
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795586 2231 243152 S259 I D V L K K N S H S Q T A L D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.9 98 92 N.A. 89.7 43.5 N.A. 27.2 51.2 48.8 21 N.A. N.A. 25.6 N.A. 25.8
Protein Similarity: 100 91.9 98.1 94 N.A. 91.7 56.2 N.A. 30.1 60.9 60.1 36 N.A. N.A. 38 N.A. 35.8
P-Site Identity: 100 20 100 100 N.A. 100 60 N.A. 0 100 100 53.3 N.A. N.A. 0 N.A. 53.3
P-Site Similarity: 100 26.6 100 100 N.A. 100 86.6 N.A. 0 100 100 73.3 N.A. N.A. 0 N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 25 0 0 0 0 0 0 0 0 0 75 0 0 % A
% Cys: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 0 67 0 0 9 0 9 0 0 0 0 0 0 0 84 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 9 0 0 0 0 0 9 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 9 0 0 0 9 0 0 % H
% Ile: 25 0 0 0 59 0 9 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 9 9 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 9 0 0 0 0 0 9 0 0 0 75 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 59 0 0 67 0 0 50 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % P
% Gln: 0 0 0 9 0 0 0 0 9 0 67 9 0 0 0 % Q
% Arg: 0 9 0 0 0 67 0 0 0 0 9 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 9 0 17 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 67 0 0 0 75 0 0 0 % T
% Val: 59 0 59 0 9 9 0 0 9 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 59 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _