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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASKIN2
All Species:
19.7
Human Site:
T331
Identified Species:
39.39
UniProt:
Q8WXE0
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WXE0
NP_001136115.1
1202
126711
T331
I
H
E
S
Q
R
G
T
D
R
I
G
Y
F
P
Chimpanzee
Pan troglodytes
XP_001137464
1108
116473
Y290
E
P
P
H
P
L
T
Y
S
Q
L
P
R
V
G
Rhesus Macaque
Macaca mulatta
XP_001097098
1204
126819
T331
I
H
E
S
Q
R
G
T
D
R
I
G
Y
F
P
Dog
Lupus familis
XP_540433
1202
126911
T331
I
H
E
S
Q
R
G
T
D
R
V
G
Y
F
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHK1
1201
126791
T331
I
H
E
S
Q
R
G
T
D
R
V
G
Y
F
P
Rat
Rattus norvegicus
Q8VHK2
1430
150329
N331
I
H
D
N
R
T
G
N
D
R
V
G
Y
F
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507411
400
42074
Chicken
Gallus gallus
XP_420128
1488
159878
R348
I
A
E
V
I
S
K
R
I
G
M
I
L
P
R
Frog
Xenopus laevis
Q6DD51
1205
130900
T331
I
H
D
P
Q
K
G
T
D
R
V
G
F
F
P
Zebra Danio
Brachydanio rerio
A5PMU4
1280
141475
T377
S
D
E
E
R
N
G
T
L
T
R
I
N
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392417
814
88839
G14
L
L
E
A
A
R
N
G
N
V
T
V
V
E
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795586
2231
243152
V336
G
S
I
M
K
G
G
V
E
S
I
G
Y
F
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.9
98
92
N.A.
89.7
43.5
N.A.
27.2
51.2
48.8
21
N.A.
N.A.
25.6
N.A.
25.8
Protein Similarity:
100
91.9
98.1
94
N.A.
91.7
56.2
N.A.
30.1
60.9
60.1
36
N.A.
N.A.
38
N.A.
35.8
P-Site Identity:
100
0
100
93.3
N.A.
93.3
60
N.A.
0
13.3
66.6
20
N.A.
N.A.
13.3
N.A.
40
P-Site Similarity:
100
13.3
100
100
N.A.
100
86.6
N.A.
0
20
93.3
26.6
N.A.
N.A.
33.3
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
9
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
17
0
0
0
0
0
50
0
0
0
0
0
0
% D
% Glu:
9
0
59
9
0
0
0
0
9
0
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
9
59
0
% F
% Gly:
9
0
0
0
0
9
67
9
0
9
0
59
0
0
9
% G
% His:
0
50
0
9
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
59
0
9
0
9
0
0
0
9
0
25
17
0
0
0
% I
% Lys:
0
0
0
0
9
9
9
0
0
0
0
0
0
9
9
% K
% Leu:
9
9
0
0
0
9
0
0
9
0
9
0
9
0
0
% L
% Met:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
9
0
9
9
9
9
0
0
0
9
0
0
% N
% Pro:
0
9
9
9
9
0
0
0
0
0
0
9
0
9
59
% P
% Gln:
0
0
0
0
42
0
0
0
0
9
0
0
0
0
0
% Q
% Arg:
0
0
0
0
17
42
0
9
0
50
9
0
9
0
17
% R
% Ser:
9
9
0
34
0
9
0
0
9
9
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
9
9
50
0
9
9
0
0
0
0
% T
% Val:
0
0
0
9
0
0
0
9
0
9
34
9
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
0
0
50
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _