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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASKIN2
All Species:
20.91
Human Site:
Y575
Identified Species:
41.82
UniProt:
Q8WXE0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WXE0
NP_001136115.1
1202
126711
Y575
C
A
L
G
L
P
Q
Y
H
K
Q
L
V
S
S
Chimpanzee
Pan troglodytes
XP_001137464
1108
116473
L525
L
M
L
G
V
K
R
L
A
E
L
R
R
G
L
Rhesus Macaque
Macaca mulatta
XP_001097098
1204
126819
Y575
C
A
L
G
L
P
Q
Y
H
K
Q
L
V
S
S
Dog
Lupus familis
XP_540433
1202
126911
Y575
C
A
L
G
L
P
Q
Y
H
K
Q
L
V
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHK1
1201
126791
Y574
C
A
L
G
L
P
Q
Y
H
K
Q
L
V
S
S
Rat
Rattus norvegicus
Q8VHK2
1430
150329
Q594
G
I
T
K
L
G
H
Q
K
K
L
M
L
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507411
400
42074
Chicken
Gallus gallus
XP_420128
1488
159878
Y600
S
A
I
G
L
P
Q
Y
H
K
K
L
V
N
N
Frog
Xenopus laevis
Q6DD51
1205
130900
S567
E
N
G
Y
E
S
L
S
T
V
T
E
L
T
W
Zebra Danio
Brachydanio rerio
A5PMU4
1280
141475
E616
H
G
S
S
P
A
C
E
S
P
D
N
P
Y
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392417
814
88839
L249
L
L
D
R
G
V
D
L
G
I
R
D
S
R
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795586
2231
243152
Y714
R
L
L
D
L
S
Q
Y
H
N
T
L
N
T
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.9
98
92
N.A.
89.7
43.5
N.A.
27.2
51.2
48.8
21
N.A.
N.A.
25.6
N.A.
25.8
Protein Similarity:
100
91.9
98.1
94
N.A.
91.7
56.2
N.A.
30.1
60.9
60.1
36
N.A.
N.A.
38
N.A.
35.8
P-Site Identity:
100
13.3
100
100
N.A.
100
13.3
N.A.
0
66.6
0
0
N.A.
N.A.
0
N.A.
40
P-Site Similarity:
100
33.3
100
100
N.A.
100
33.3
N.A.
0
93.3
13.3
0
N.A.
N.A.
6.6
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
42
0
0
0
9
0
0
9
0
0
0
0
9
0
% A
% Cys:
34
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
9
0
0
9
0
0
0
9
9
0
0
0
% D
% Glu:
9
0
0
0
9
0
0
9
0
9
0
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
9
9
50
9
9
0
0
9
0
0
0
0
9
0
% G
% His:
9
0
0
0
0
0
9
0
50
0
0
0
0
0
0
% H
% Ile:
0
9
9
0
0
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
0
0
9
0
9
0
0
9
50
9
0
0
0
0
% K
% Leu:
17
17
50
0
59
0
9
17
0
0
17
50
17
0
9
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
9
0
9
9
9
17
% N
% Pro:
0
0
0
0
9
42
0
0
0
9
0
0
9
0
0
% P
% Gln:
0
0
0
0
0
0
50
9
0
0
34
0
0
0
17
% Q
% Arg:
9
0
0
9
0
0
9
0
0
0
9
9
9
9
0
% R
% Ser:
9
0
9
9
0
17
0
9
9
0
0
0
9
34
34
% S
% Thr:
0
0
9
0
0
0
0
0
9
0
17
0
0
17
0
% T
% Val:
0
0
0
0
9
9
0
0
0
9
0
0
42
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% W
% Tyr:
0
0
0
9
0
0
0
50
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _