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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STON2 All Species: 10.61
Human Site: S379 Identified Species: 21.21
UniProt: Q8WXE9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WXE9 NP_149095.2 905 101165 S379 S S K T Q S H S D A V E K L K
Chimpanzee Pan troglodytes XP_001135210 905 101144 S379 S S K T Q S H S D A V E K L K
Rhesus Macaque Macaca mulatta XP_001105584 896 100013 S379 S S K T Q S H S D A V E K L K
Dog Lupus familis XP_864856 735 82747 A254 L S M Q C Q Y A E D T A S S F
Cat Felis silvestris
Mouse Mus musculus Q8BZ60 895 99593 I379 S Q P H P D A I E K L K Q L Q
Rat Rattus norvegicus NP_001129346 895 99472 I379 S Q S H P D A I E K L K Q L Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505629 865 95494 D379 S R G Q T H R D A V E K L K Q
Chicken Gallus gallus XP_421302 887 99388 I379 E Q L K Q L Q I G D P D Y V S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001028915 859 96510 D378 V D E A D F T D S T Y E P H H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24212 1262 137751 T408 T T P D I E I T T V E D L P R
Honey Bee Apis mellifera XP_396872 1188 129859 D549 V K R T E S V D S D A G P D F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795059 1041 114812 Q433 F A A A A A A Q Q S A A A S Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 96.9 31.4 N.A. 86.1 85.8 N.A. 68 69.8 N.A. 48.5 N.A. 23.6 24.7 N.A. 25.5
Protein Similarity: 100 99.6 98 49.5 N.A. 90 89.7 N.A. 76.8 79.8 N.A. 61.7 N.A. 38.7 40 N.A. 44.6
P-Site Identity: 100 100 100 6.6 N.A. 13.3 13.3 N.A. 6.6 6.6 N.A. 6.6 N.A. 0 13.3 N.A. 0
P-Site Similarity: 100 100 100 26.6 N.A. 46.6 46.6 N.A. 20 20 N.A. 13.3 N.A. 33.3 26.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 17 9 9 25 9 9 25 17 17 9 0 0 % A
% Cys: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 9 9 17 0 25 25 25 0 17 0 9 0 % D
% Glu: 9 0 9 0 9 9 0 0 25 0 17 34 0 0 0 % E
% Phe: 9 0 0 0 0 9 0 0 0 0 0 0 0 0 17 % F
% Gly: 0 0 9 0 0 0 0 0 9 0 0 9 0 0 0 % G
% His: 0 0 0 17 0 9 25 0 0 0 0 0 0 9 9 % H
% Ile: 0 0 0 0 9 0 9 25 0 0 0 0 0 0 0 % I
% Lys: 0 9 25 9 0 0 0 0 0 17 0 25 25 9 25 % K
% Leu: 9 0 9 0 0 9 0 0 0 0 17 0 17 42 0 % L
% Met: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 17 0 17 0 0 0 0 0 9 0 17 9 0 % P
% Gln: 0 25 0 17 34 9 9 9 9 0 0 0 17 0 34 % Q
% Arg: 0 9 9 0 0 0 9 0 0 0 0 0 0 0 9 % R
% Ser: 50 34 9 0 0 34 0 25 17 9 0 0 9 17 9 % S
% Thr: 9 9 0 34 9 0 9 9 9 9 9 0 0 0 0 % T
% Val: 17 0 0 0 0 0 9 0 0 17 25 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 0 0 0 9 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _