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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STON2 All Species: 31.82
Human Site: S498 Identified Species: 63.64
UniProt: Q8WXE9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WXE9 NP_149095.2 905 101165 S498 D E N G R I H S L R I D R V T
Chimpanzee Pan troglodytes XP_001135210 905 101144 S498 D E N G R I H S L R I D R V T
Rhesus Macaque Macaca mulatta XP_001105584 896 100013 S498 D E N G R I H S L R I D R V T
Dog Lupus familis XP_864856 735 82747 E355 I E H V S Y T E K R K Y H S K
Cat Felis silvestris
Mouse Mus musculus Q8BZ60 895 99593 S495 D E N G R I H S L R I D R V T
Rat Rattus norvegicus NP_001129346 895 99472 S495 D E N G R I H S L R I D R V T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505629 865 95494 E480 F K L E I S H E I S E P K L Q
Chicken Gallus gallus XP_421302 887 99388 S487 D E N G R I H S V R L D R T T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001028915 859 96510 K479 E K R K I Q P K V T V V H L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24212 1262 137751 T802 D Q F G K I F T M K L Q Y I F
Honey Bee Apis mellifera XP_396872 1188 129859 T728 D Q Y G K I F T V K L Q Y I F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795059 1041 114812 T651 D A K G K I H T V K L L Y M S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 96.9 31.4 N.A. 86.1 85.8 N.A. 68 69.8 N.A. 48.5 N.A. 23.6 24.7 N.A. 25.5
Protein Similarity: 100 99.6 98 49.5 N.A. 90 89.7 N.A. 76.8 79.8 N.A. 61.7 N.A. 38.7 40 N.A. 44.6
P-Site Identity: 100 100 100 13.3 N.A. 100 100 N.A. 6.6 80 N.A. 0 N.A. 20 20 N.A. 26.6
P-Site Similarity: 100 100 100 20 N.A. 100 100 N.A. 33.3 93.3 N.A. 33.3 N.A. 66.6 66.6 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 75 0 0 0 0 0 0 0 0 0 0 50 0 0 0 % D
% Glu: 9 59 0 9 0 0 0 17 0 0 9 0 0 0 0 % E
% Phe: 9 0 9 0 0 0 17 0 0 0 0 0 0 0 17 % F
% Gly: 0 0 0 75 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 9 0 0 0 67 0 0 0 0 0 17 0 0 % H
% Ile: 9 0 0 0 17 75 0 0 9 0 42 0 0 17 0 % I
% Lys: 0 17 9 9 25 0 0 9 9 25 9 0 9 0 9 % K
% Leu: 0 0 9 0 0 0 0 0 42 0 34 9 0 17 0 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 0 9 0 % M
% Asn: 0 0 50 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 9 0 0 0 0 9 0 0 9 % P
% Gln: 0 17 0 0 0 9 0 0 0 0 0 17 0 0 9 % Q
% Arg: 0 0 9 0 50 0 0 0 0 59 0 0 50 0 0 % R
% Ser: 0 0 0 0 9 9 0 50 0 9 0 0 0 9 9 % S
% Thr: 0 0 0 0 0 0 9 25 0 9 0 0 0 9 50 % T
% Val: 0 0 0 9 0 0 0 0 34 0 9 9 0 42 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 9 0 0 0 0 0 9 25 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _