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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STON2 All Species: 8.48
Human Site: S695 Identified Species: 16.97
UniProt: Q8WXE9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WXE9 NP_149095.2 905 101165 S695 F T L R T A T S V N G A E V E
Chimpanzee Pan troglodytes XP_001135210 905 101144 S695 F T L R T A A S V N G A E V E
Rhesus Macaque Macaca mulatta XP_001105584 896 100013 K684 F R T V F A E K T L P F T L R
Dog Lupus familis XP_864856 735 82747 L526 T L Y G G E D L P F T L K S V
Cat Felis silvestris
Mouse Mus musculus Q8BZ60 895 99593 T686 A E K T L P F T L R T A A S I
Rat Rattus norvegicus NP_001129346 895 99472 T686 A E K T L P F T L R T A A S I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505629 865 95494 S656 C V D E D A F S S S R A I L F
Chicken Gallus gallus XP_421302 887 99388 T678 A E K T L P F T L R T A A S I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001028915 859 96510 P650 P F A E K T L P F T L R T V A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24212 1262 137751 G1036 K A T W C V S G N K V E L R A
Honey Bee Apis mellifera XP_396872 1188 129859 G962 K A V M C I T G N K V E L R A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795059 1041 114812 E831 Q F H I Q P S E E E D L P L Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 96.9 31.4 N.A. 86.1 85.8 N.A. 68 69.8 N.A. 48.5 N.A. 23.6 24.7 N.A. 25.5
Protein Similarity: 100 99.6 98 49.5 N.A. 90 89.7 N.A. 76.8 79.8 N.A. 61.7 N.A. 38.7 40 N.A. 44.6
P-Site Identity: 100 93.3 13.3 0 N.A. 6.6 6.6 N.A. 20 6.6 N.A. 6.6 N.A. 0 6.6 N.A. 0
P-Site Similarity: 100 93.3 20 6.6 N.A. 20 20 N.A. 33.3 20 N.A. 6.6 N.A. 6.6 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 17 9 0 0 34 9 0 0 0 0 50 25 0 25 % A
% Cys: 9 0 0 0 17 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 9 0 9 0 0 0 9 0 0 0 0 % D
% Glu: 0 25 0 17 0 9 9 9 9 9 0 17 17 0 17 % E
% Phe: 25 17 0 0 9 0 34 0 9 9 0 9 0 0 9 % F
% Gly: 0 0 0 9 9 0 0 17 0 0 17 0 0 0 0 % G
% His: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 9 0 9 0 0 0 0 0 0 9 0 25 % I
% Lys: 17 0 25 0 9 0 0 9 0 17 0 0 9 0 0 % K
% Leu: 0 9 17 0 25 0 9 9 25 9 9 17 17 25 0 % L
% Met: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 17 17 0 0 0 0 0 % N
% Pro: 9 0 0 0 0 34 0 9 9 0 9 0 9 0 0 % P
% Gln: 9 0 0 0 9 0 0 0 0 0 0 0 0 0 9 % Q
% Arg: 0 9 0 17 0 0 0 0 0 25 9 9 0 17 9 % R
% Ser: 0 0 0 0 0 0 17 25 9 9 0 0 0 34 0 % S
% Thr: 9 17 17 25 17 9 17 25 9 9 34 0 17 0 0 % T
% Val: 0 9 9 9 0 9 0 0 17 0 17 0 0 25 9 % V
% Trp: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _