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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRRP35
All Species:
12.42
Human Site:
S217
Identified Species:
22.78
UniProt:
Q8WXF0
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WXF0
NP_542781.3
261
30512
S217
S
R
S
H
G
R
H
S
D
S
I
A
R
S
P
Chimpanzee
Pan troglodytes
Q5R1W5
221
25469
R178
S
K
S
S
S
V
S
R
S
R
S
R
S
R
S
Rhesus Macaque
Macaca mulatta
XP_001095016
267
31240
S223
S
R
S
H
G
R
H
S
D
S
I
A
R
S
P
Dog
Lupus familis
XP_532229
326
36990
S282
S
R
S
H
G
R
H
S
D
S
I
A
R
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q62093
221
25458
R178
S
K
S
S
S
V
S
R
S
R
S
R
S
R
S
Rat
Rattus norvegicus
NP_001129183
261
30354
C217
P
R
S
H
G
R
H
C
D
S
I
A
R
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P30352
221
25506
R178
S
K
S
S
S
V
S
R
S
R
S
R
S
R
S
Frog
Xenopus laevis
NP_001088237
251
29229
H208
R
S
G
S
N
R
S
H
S
K
S
P
H
H
R
Zebra Danio
Brachydanio rerio
Q7SXP4
257
28365
S214
R
S
P
S
Y
G
R
S
R
S
R
S
R
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q02427
144
15994
G101
G
G
S
S
G
R
S
G
S
G
R
Y
R
I
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09511
196
22569
P153
S
R
D
R
R
D
S
P
D
R
R
D
N
S
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001151991
209
24579
N166
Y
S
R
S
P
P
Q
N
P
R
H
R
L
R
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22315
303
33711
S240
S
R
S
P
K
A
K
S
S
R
R
S
P
A
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.9
97.7
75.4
N.A.
37.9
90.8
N.A.
N.A.
39
62
22.2
N.A.
22.9
N.A.
35.6
N.A.
Protein Similarity:
100
50.9
97.7
76.9
N.A.
51.7
94.2
N.A.
N.A.
51.7
69.3
37.5
N.A.
34.4
N.A.
47.1
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
13.3
86.6
N.A.
N.A.
13.3
6.6
26.6
N.A.
26.6
N.A.
26.6
N.A.
P-Site Similarity:
100
20
100
100
N.A.
20
86.6
N.A.
N.A.
20
6.6
33.3
N.A.
26.6
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
22.9
N.A.
27.7
N.A.
N.A.
Protein Similarity:
N.A.
35.6
N.A.
44.5
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
0
0
31
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
8
0
0
39
0
0
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
8
0
39
8
0
8
0
8
0
0
0
0
0
% G
% His:
0
0
0
31
0
0
31
8
0
0
8
0
8
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
31
0
0
8
0
% I
% Lys:
0
24
0
0
8
0
8
0
0
8
0
0
0
0
8
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
8
0
0
0
0
8
0
0
% N
% Pro:
8
0
8
8
8
8
0
8
8
0
0
8
8
0
31
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
16
47
8
8
8
47
8
24
8
47
31
31
47
31
24
% R
% Ser:
62
24
70
54
24
0
47
39
47
39
31
16
24
47
24
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% T
% Val:
0
0
0
0
0
24
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _