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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEDD2
All Species:
10.3
Human Site:
S189
Identified Species:
28.33
UniProt:
Q8WXF8
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WXF8
NP_579874.1
326
36179
S189
Q
S
E
P
A
R
P
S
S
E
G
K
V
T
C
Chimpanzee
Pan troglodytes
XP_530083
326
36100
S189
Q
P
E
P
A
R
P
S
S
E
G
K
V
T
C
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_855274
329
36585
V192
Q
Q
E
P
A
R
P
V
S
E
G
K
V
T
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8QZV0
330
36768
S193
H
Q
E
L
G
R
P
S
S
E
G
K
V
T
C
Rat
Rattus norvegicus
Q9Z2K0
318
36829
D186
R
R
K
S
V
T
P
D
P
K
E
K
Q
T
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520660
116
12937
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088715
357
40839
T226
N
T
P
L
Q
N
P
T
N
Q
S
K
V
T
C
Zebra Danio
Brachydanio rerio
NP_001002639
404
44870
D261
K
R
S
H
T
T
A
D
C
R
E
K
Q
T
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198205
159
18300
V31
R
H
D
L
M
P
F
V
T
R
R
K
R
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
N.A.
94.2
N.A.
92.1
40.7
N.A.
31.2
N.A.
48.7
31.6
N.A.
N.A.
N.A.
N.A.
30.3
Protein Similarity:
100
98.7
N.A.
95.1
N.A.
93.9
57.6
N.A.
32.5
N.A.
62.7
47
N.A.
N.A.
N.A.
N.A.
38.3
P-Site Identity:
100
93.3
N.A.
86.6
N.A.
73.3
26.6
N.A.
0
N.A.
33.3
20
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
N.A.
86.6
N.A.
73.3
46.6
N.A.
0
N.A.
60
26.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
34
0
12
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
78
% C
% Asp:
0
0
12
0
0
0
0
23
0
0
0
0
0
0
0
% D
% Glu:
0
0
45
0
0
0
0
0
0
45
23
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
12
0
0
0
0
0
45
0
0
0
0
% G
% His:
12
12
0
12
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
0
12
0
0
0
0
0
0
12
0
89
0
12
0
% K
% Leu:
0
0
0
34
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
12
0
0
12
0
0
0
0
0
0
% N
% Pro:
0
12
12
34
0
12
67
0
12
0
0
0
0
0
0
% P
% Gln:
34
23
0
0
12
0
0
0
0
12
0
0
23
0
0
% Q
% Arg:
23
23
0
0
0
45
0
0
0
23
12
0
12
0
12
% R
% Ser:
0
12
12
12
0
0
0
34
45
0
12
0
0
0
0
% S
% Thr:
0
12
0
0
12
23
0
12
12
0
0
0
0
78
0
% T
% Val:
0
0
0
0
12
0
0
23
0
0
0
0
56
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _