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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MADD All Species: 22.12
Human Site: T175 Identified Species: 69.52
UniProt: Q8WXG6 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WXG6 NP_001129415.1 1647 183303 T175 R S R N S T L T S L C V L S H
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001107325 1647 183326 T175 R S R N S T L T S L C V L S H
Dog Lupus familis XP_850209 1648 183311 L175 S R S R N S T L T S L C V L S
Cat Felis silvestris
Mouse Mus musculus Q80U28 1577 175161 T174 R S R N S T L T S L C V L S H
Rat Rattus norvegicus O08873 1602 177973 T174 R S R N S T L T S L C V L S H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421109 1650 184309 T181 R S R N S T L T S L C I L S H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXY2 2075 224878 T227 K L R N Q S L T S L C I I S H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O02626 1409 157440 E71 V T V F C Q P E G C T T T S A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.8 96.9 N.A. 91.5 93 N.A. N.A. 84.3 N.A. N.A. N.A. 32.8 N.A. 37 N.A.
Protein Similarity: 100 N.A. 99.2 98.1 N.A. 93 94.7 N.A. N.A. 90.7 N.A. N.A. N.A. 45.9 N.A. 53.7 N.A.
P-Site Identity: 100 N.A. 100 0 N.A. 100 100 N.A. N.A. 93.3 N.A. N.A. N.A. 60 N.A. 6.6 N.A.
P-Site Similarity: 100 N.A. 100 26.6 N.A. 100 100 N.A. N.A. 100 N.A. N.A. N.A. 86.6 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % A
% Cys: 0 0 0 0 13 0 0 0 0 13 75 13 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 75 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 25 13 0 0 % I
% Lys: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 13 0 0 0 0 75 13 0 75 13 0 63 13 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 75 13 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 13 13 0 0 0 0 0 0 0 0 0 % Q
% Arg: 63 13 75 13 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 13 63 13 0 63 25 0 0 75 13 0 0 0 88 13 % S
% Thr: 0 13 0 0 0 63 13 75 13 0 13 13 13 0 0 % T
% Val: 13 0 13 0 0 0 0 0 0 0 0 50 13 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _