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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CPA5 All Species: 39.7
Human Site: S395 Identified Species: 72.78
UniProt: Q8WXQ8 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WXQ8 NP_001120913.1 436 49036 S395 S G I K Y A F S F E L R D T G
Chimpanzee Pan troglodytes XP_001145510 852 95546 S448 S G I K Y A F S F E L R D T G
Rhesus Macaque Macaca mulatta XP_001095669 436 49100 S395 S G I K Y A F S F E L R D T G
Dog Lupus familis XP_848779 436 49141 T395 N G I K Y S F T F E L R D T G
Cat Felis silvestris
Mouse Mus musculus Q8R4H4 436 49133 S395 S G I K Y A F S F E L R D T G
Rat Rattus norvegicus P00731 419 47179 T378 Q G I K Y S F T F E L R D T G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511176 419 47004 T378 N G I K Y S F T F E L R D T G
Chicken Gallus gallus NP_989915 419 46988 T378 Q G I K Y S F T F E L R D T G
Frog Xenopus laevis NP_001079924 416 47094 T375 Q G I K H S Y T F E L R D T G
Zebra Danio Brachydanio rerio NP_001018318 418 47401 F378 G I K Y S Y T F E L R D T G R
Tiger Blowfish Takifugu rubipres NP_001163829 452 50806 T411 Q G I K Y S Y T F E L R D T G
Fruit Fly Dros. melanogaster Q9VL86 430 47642 F383 T Q D V R M A F C Y E L R P S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38836 430 49811 Q389 H R A H W A F Q L K L R D T G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 50.4 96.3 87.6 N.A. 84.1 56.8 N.A. 62.8 54.5 53.6 54.3 53.9 28.8 N.A. N.A. N.A.
Protein Similarity: 100 50.8 97.9 94.9 N.A. 91 73.1 N.A. 79.5 71.7 71.3 72 69.6 52.7 N.A. N.A. N.A.
P-Site Identity: 100 100 100 80 N.A. 100 80 N.A. 80 80 66.6 0 73.3 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. 100 93.3 93.3 0 93.3 6.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 48.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 39 8 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 0 0 0 0 0 8 85 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 8 77 8 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 70 16 77 0 0 0 0 0 0 % F
% Gly: 8 77 0 0 0 0 0 0 0 0 0 0 0 8 85 % G
% His: 8 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 77 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 8 77 0 0 0 0 0 8 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 8 8 85 8 0 0 0 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % P
% Gln: 31 8 0 0 0 0 0 8 0 0 0 0 0 0 0 % Q
% Arg: 0 8 0 0 8 0 0 0 0 0 8 85 8 0 8 % R
% Ser: 31 0 0 0 8 47 0 31 0 0 0 0 0 0 8 % S
% Thr: 8 0 0 0 0 0 8 47 0 0 0 0 8 85 0 % T
% Val: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 70 8 16 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _