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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAMTS14
All Species:
16.36
Human Site:
Y849
Identified Species:
45
UniProt:
Q8WXS8
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WXS8
NP_542453.2
1223
133872
Y849
L
L
E
E
M
D
T
Y
E
W
A
L
K
S
W
Chimpanzee
Pan troglodytes
XP_507838
1223
133736
Y849
L
L
E
E
M
D
T
Y
E
W
A
L
K
S
W
Rhesus Macaque
Macaca mulatta
XP_001107840
1223
133969
Y849
L
L
E
E
T
D
T
Y
E
W
A
L
K
S
W
Dog
Lupus familis
XP_546149
1224
134775
Y850
L
L
E
E
T
D
T
Y
E
W
A
L
K
S
W
Cat
Felis silvestris
Mouse
Mus musculus
Q8C9W3
1213
135281
H857
L
E
D
D
A
V
R
H
E
W
A
L
K
K
W
Rat
Rattus norvegicus
Q1EHB3
1595
175796
A861
C
N
E
E
P
C
P
A
R
W
W
V
G
D
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505715
1189
133383
Y835
L
V
E
L
S
V
S
Y
E
W
A
L
K
K
W
Chicken
Gallus gallus
XP_426316
1212
136699
F851
L
Q
E
E
I
D
T
F
E
W
A
L
K
S
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_697234
1164
131811
D834
N
N
N
V
I
Q
E
D
T
Y
E
W
A
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.8
87.4
N.A.
50.2
24.9
N.A.
50.6
52.2
N.A.
52
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
97.2
90.7
N.A.
64.5
37.4
N.A.
65.9
65.2
N.A.
65.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
46.6
26.6
N.A.
60
80
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
66.6
33.3
N.A.
73.3
93.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
0
12
0
0
78
0
12
0
0
% A
% Cys:
12
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
12
0
56
0
12
0
0
0
0
0
12
0
% D
% Glu:
0
12
78
67
0
0
12
0
78
0
12
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% G
% His:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
23
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
78
23
12
% K
% Leu:
78
45
0
12
0
0
0
0
0
0
0
78
0
12
0
% L
% Met:
0
0
0
0
23
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
23
12
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
12
0
12
0
0
0
0
0
0
0
0
% P
% Gln:
0
12
0
0
0
12
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
12
0
12
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
12
0
12
0
0
0
0
0
0
56
0
% S
% Thr:
0
0
0
0
23
0
56
0
12
0
0
0
0
0
0
% T
% Val:
0
12
0
12
0
23
0
0
0
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
89
12
12
0
0
89
% W
% Tyr:
0
0
0
0
0
0
0
56
0
12
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _