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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FOXD4L4 All Species: 32.42
Human Site: Y144 Identified Species: 71.33
UniProt: Q8WXT5 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WXT5 NP_001092749.1 416 45892 Y144 F I S G R F P Y Y R R K F P A
Chimpanzee Pan troglodytes NP_001009014 413 45421 Y140 F I S G R F P Y Y R R K F P A
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q60688 444 48029 Y139 F I S G R F P Y Y R R K F P A
Rat Rattus norvegicus Q63245 101 11924
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516678 728 77542 Y262 F I S G R F P Y Y R R K F P A
Chicken Gallus gallus P79772 394 40977 Y153 F I S N R F P Y Y R E K F P A
Frog Xenopus laevis Q9DEN4 371 40000 Y130 F I S N R F P Y Y R E K F P A
Zebra Danio Brachydanio rerio NP_571365 371 40457 Y132 F I S N R F P Y Y R E K F P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q02361 456 49036 Y121 F I M S R F P Y Y K D K F P A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_496411 333 37274 D110 K D D D D D D D S T S R K S M
Sea Urchin Strong. purpuratus XP_001188749 401 43606 Y154 F I M N R F P Y Y R E K F P V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.8 N.A. N.A. N.A. 50 21.6 N.A. 31.8 39.1 36.5 36 N.A. 30.7 N.A. 30.5 32.2
Protein Similarity: 100 96.8 N.A. N.A. N.A. 58.3 23 N.A. 38.7 48.7 48.3 48 N.A. 42.1 N.A. 45.6 44.4
P-Site Identity: 100 100 N.A. N.A. N.A. 100 0 N.A. 100 86.6 86.6 86.6 N.A. 73.3 N.A. 0 73.3
P-Site Similarity: 100 100 N.A. N.A. N.A. 100 0 N.A. 100 86.6 86.6 86.6 N.A. 80 N.A. 6.6 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 73 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 10 10 10 10 10 10 0 0 10 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 37 0 0 0 0 % E
% Phe: 82 0 0 0 0 82 0 0 0 0 0 0 82 0 0 % F
% Gly: 0 0 0 37 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 82 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 0 0 0 0 0 0 10 0 82 10 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 19 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 37 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 82 0 0 0 0 0 0 82 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 82 0 0 0 0 73 37 10 0 0 0 % R
% Ser: 0 0 64 10 0 0 0 0 10 0 10 0 0 10 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 82 82 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _