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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DYX1C1
All Species:
6.36
Human Site:
S131
Identified Species:
14
UniProt:
Q8WXU2
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WXU2
NP_001028731.1
420
48527
S131
E
D
Q
K
Y
A
L
S
V
M
M
K
I
E
E
Chimpanzee
Pan troglodytes
Q863A7
420
48596
S131
E
D
Q
K
Y
A
L
S
V
M
M
K
I
E
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_544692
420
48639
N131
E
D
Q
K
Y
A
L
N
V
M
M
K
I
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8R368
420
48222
G131
E
D
Q
R
Y
A
L
G
E
M
M
K
I
E
E
Rat
Rattus norvegicus
NP_001007011
420
48101
G131
E
D
Q
R
Y
A
L
G
E
M
M
K
I
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514345
358
41501
Q123
E
K
L
R
Q
Q
K
Q
Q
L
E
E
E
R
K
Chicken
Gallus gallus
NP_001008674
423
48707
E131
E
H
K
K
Y
A
L
E
A
T
M
K
L
E
E
Frog
Xenopus laevis
NP_001086864
421
48197
E131
E
N
E
K
Y
S
L
E
V
T
M
K
I
D
E
Zebra Danio
Brachydanio rerio
NP_991251
420
47994
T131
E
K
K
Y
A
L
E
T
M
M
K
L
E
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394979
348
40259
E114
X
N
E
M
I
V
K
E
E
D
N
K
N
D
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787717
397
45886
L131
R
E
K
E
K
L
A
L
N
E
Q
M
R
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
88
N.A.
79.2
80.4
N.A.
62.1
65.2
61.7
54.7
N.A.
N.A.
35.9
N.A.
45
Protein Similarity:
100
99.5
N.A.
94.5
N.A.
88
89
N.A.
74
80.6
76.9
72.6
N.A.
N.A.
53.8
N.A.
65.2
P-Site Identity:
100
100
N.A.
93.3
N.A.
80
80
N.A.
6.6
60
60
20
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
86.6
86.6
N.A.
33.3
73.3
86.6
40
N.A.
N.A.
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
55
10
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
46
0
0
0
0
0
0
0
10
0
0
0
19
0
% D
% Glu:
82
10
19
10
0
0
10
28
28
10
10
10
19
55
82
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
55
0
10
% I
% Lys:
0
19
28
46
10
0
19
0
0
0
10
73
0
0
10
% K
% Leu:
0
0
10
0
0
19
64
10
0
10
0
10
10
10
0
% L
% Met:
0
0
0
10
0
0
0
0
10
55
64
10
0
0
0
% M
% Asn:
0
19
0
0
0
0
0
10
10
0
10
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
46
0
10
10
0
10
10
0
10
0
0
0
0
% Q
% Arg:
10
0
0
28
0
0
0
0
0
0
0
0
10
10
0
% R
% Ser:
0
0
0
0
0
10
0
19
0
0
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
19
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
37
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
64
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _