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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DYX1C1
All Species:
12.73
Human Site:
S398
Identified Species:
28
UniProt:
Q8WXU2
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WXU2
NP_001028731.1
420
48527
S398
A
A
L
K
I
D
P
S
N
K
I
V
Q
I
D
Chimpanzee
Pan troglodytes
Q863A7
420
48596
S398
A
A
L
K
I
D
P
S
N
K
I
V
Q
I
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_544692
420
48639
S398
A
A
L
K
I
D
P
S
N
K
I
V
Q
N
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8R368
420
48222
A396
A
A
L
K
I
D
P
A
N
T
V
V
Q
N
D
Rat
Rattus norvegicus
NP_001007011
420
48101
A396
A
A
L
K
I
D
P
A
N
T
V
V
Q
N
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514345
358
41501
K340
L
K
I
D
P
S
N
K
I
V
E
Q
D
A
E
Chicken
Gallus gallus
NP_001008674
423
48707
K401
A
A
L
K
I
D
P
K
N
K
T
I
E
K
D
Frog
Xenopus laevis
NP_001086864
421
48197
T388
A
A
L
K
I
D
P
T
N
Q
N
M
K
S
D
Zebra Danio
Brachydanio rerio
NP_991251
420
47994
H394
K
A
L
E
M
D
P
H
N
A
A
L
R
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394979
348
40259
N330
A
L
K
L
T
P
N
N
E
S
I
K
R
D
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787717
397
45886
K378
A
A
L
K
I
E
P
K
N
E
Q
L
R
Q
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
88
N.A.
79.2
80.4
N.A.
62.1
65.2
61.7
54.7
N.A.
N.A.
35.9
N.A.
45
Protein Similarity:
100
99.5
N.A.
94.5
N.A.
88
89
N.A.
74
80.6
76.9
72.6
N.A.
N.A.
53.8
N.A.
65.2
P-Site Identity:
100
100
N.A.
93.3
N.A.
73.3
73.3
N.A.
0
66.6
60
40
N.A.
N.A.
13.3
N.A.
53.3
P-Site Similarity:
100
100
N.A.
93.3
N.A.
86.6
86.6
N.A.
13.3
80
86.6
66.6
N.A.
N.A.
26.6
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
82
82
0
0
0
0
0
19
0
10
10
0
0
19
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
73
0
0
0
0
0
0
10
10
82
% D
% Glu:
0
0
0
10
0
10
0
0
10
10
10
0
10
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
73
0
0
0
10
0
37
10
0
19
0
% I
% Lys:
10
10
10
73
0
0
0
28
0
37
0
10
10
10
0
% K
% Leu:
10
10
82
10
0
0
0
0
0
0
0
19
0
0
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
19
10
82
0
10
0
0
28
0
% N
% Pro:
0
0
0
0
10
10
82
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
10
10
46
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
28
0
0
% R
% Ser:
0
0
0
0
0
10
0
28
0
10
0
0
0
10
0
% S
% Thr:
0
0
0
0
10
0
0
10
0
19
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
19
46
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _