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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC7A3
All Species:
9.7
Human Site:
T451
Identified Species:
26.67
UniProt:
Q8WY07
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WY07
NP_001041629.1
619
67169
T451
L
Q
E
E
A
I
T
T
E
S
E
K
L
T
L
Chimpanzee
Pan troglodytes
XP_001139004
629
67650
A453
T
S
D
E
L
D
P
A
D
Q
N
E
L
A
S
Rhesus Macaque
Macaca mulatta
XP_001085167
619
67027
T451
L
Q
E
E
P
I
T
T
E
S
E
K
L
T
L
Dog
Lupus familis
XP_549065
617
66531
A451
Q
E
E
N
M
A
G
A
E
K
L
T
L
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
P70423
618
67441
E451
E
L
Q
E
E
T
L
E
A
E
K
L
T
V
Q
Rat
Rattus norvegicus
O08812
619
67506
L451
E
L
Q
E
E
R
T
L
E
A
E
K
L
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
B3TP03
654
71198
S454
E
K
A
T
L
A
A
S
K
R
E
S
A
V
S
Frog
Xenopus laevis
Q6DCE8
622
66913
S455
L
Q
E
Q
N
I
S
S
I
S
H
L
P
E
T
Zebra Danio
Brachydanio rerio
Q5PR34
640
69447
S453
G
K
E
E
V
G
E
S
E
L
T
E
S
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.7
97
88
N.A.
81.7
83.5
N.A.
N.A.
55
56.2
55.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
74
98.3
93.2
N.A.
90.7
90.9
N.A.
N.A.
70.9
73.4
70.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
93.3
20
N.A.
6.6
46.6
N.A.
N.A.
6.6
33.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
93.3
26.6
N.A.
20
66.6
N.A.
N.A.
26.6
53.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
12
23
12
23
12
12
0
0
12
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
0
0
12
0
0
12
0
0
0
0
0
0
% D
% Glu:
34
12
56
67
23
0
12
12
56
12
45
23
0
23
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
0
0
0
12
12
0
0
0
0
0
0
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% H
% Ile:
0
0
0
0
0
34
0
0
12
0
0
0
0
0
0
% I
% Lys:
0
23
0
0
0
0
0
0
12
12
12
34
0
0
0
% K
% Leu:
34
23
0
0
23
0
12
12
0
12
12
23
56
0
23
% L
% Met:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
12
0
0
0
0
0
12
0
0
0
0
% N
% Pro:
0
0
0
0
12
0
12
0
0
0
0
0
12
0
0
% P
% Gln:
12
34
23
12
0
0
0
0
0
12
0
0
0
12
12
% Q
% Arg:
0
0
0
0
0
12
0
0
0
12
0
0
0
0
0
% R
% Ser:
0
12
0
0
0
0
12
34
0
34
0
12
12
0
34
% S
% Thr:
12
0
0
12
0
12
34
23
0
0
12
12
12
34
12
% T
% Val:
0
0
0
0
12
0
0
0
0
0
0
0
0
23
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _