KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1E
All Species:
12.42
Human Site:
S570
Identified Species:
30.37
UniProt:
Q8WY54
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WY54
NP_055721.3
766
85242
S570
R
T
S
L
S
P
G
S
Q
I
N
V
L
E
D
Chimpanzee
Pan troglodytes
XP_523813
716
80142
S520
R
T
S
L
S
P
G
S
Q
I
N
V
L
E
D
Rhesus Macaque
Macaca mulatta
XP_001089477
455
49874
D275
L
H
V
A
W
L
G
D
S
Q
V
I
L
V
Q
Dog
Lupus familis
XP_853253
755
84128
S558
R
T
S
L
S
P
G
S
Q
I
N
V
L
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q80TL0
749
83400
P556
R
T
S
L
S
P
G
P
Q
I
N
V
L
E
D
Rat
Rattus norvegicus
Q80Z30
750
83420
P556
R
T
S
L
S
P
G
P
Q
I
N
V
L
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509388
612
67716
G432
D
L
A
G
A
N
P
G
R
P
P
S
A
G
W
Chicken
Gallus gallus
XP_415871
725
79898
S526
R
T
S
L
S
I
G
S
G
I
N
P
F
D
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001018354
633
71021
G450
E
L
V
C
Q
D
G
G
A
E
N
G
G
K
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202833
645
70404
I458
A
N
A
N
N
N
N
I
N
R
N
S
G
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.3
30.4
88.5
N.A.
88.3
87.7
N.A.
61.7
67.7
N.A.
42.4
N.A.
N.A.
N.A.
N.A.
27.9
Protein Similarity:
100
92.8
40.3
91.2
N.A.
91.9
90.7
N.A.
67
75.7
N.A.
55
N.A.
N.A.
N.A.
N.A.
43
P-Site Identity:
100
100
13.3
100
N.A.
93.3
93.3
N.A.
0
66.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
20
100
N.A.
93.3
93.3
N.A.
20
73.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
20
10
10
0
0
0
10
0
0
0
10
0
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
10
0
10
0
0
0
0
0
10
60
% D
% Glu:
10
0
0
0
0
0
0
0
0
10
0
0
0
50
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
10
0
0
80
20
10
0
0
10
20
10
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
10
0
60
0
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% K
% Leu:
10
20
0
60
0
10
0
0
0
0
0
0
60
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
10
10
20
10
0
10
0
80
0
0
0
10
% N
% Pro:
0
0
0
0
0
50
10
20
0
10
10
10
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
50
10
0
0
0
0
10
% Q
% Arg:
60
0
0
0
0
0
0
0
10
10
0
0
0
10
0
% R
% Ser:
0
0
60
0
60
0
0
40
10
0
0
20
0
0
0
% S
% Thr:
0
60
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
20
0
0
0
0
0
0
0
10
50
0
10
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _