KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1E
All Species:
20.91
Human Site:
S589
Identified Species:
51.11
UniProt:
Q8WY54
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WY54
NP_055721.3
766
85242
S589
D
L
T
Q
I
E
A
S
K
P
H
S
A
Q
F
Chimpanzee
Pan troglodytes
XP_523813
716
80142
S539
D
L
T
Q
I
E
A
S
K
P
H
S
A
Q
F
Rhesus Macaque
Macaca mulatta
XP_001089477
455
49874
R294
V
K
L
M
E
P
H
R
P
E
R
Q
D
E
K
Dog
Lupus familis
XP_853253
755
84128
S577
D
L
T
Q
I
E
A
S
K
P
H
S
A
Q
F
Cat
Felis silvestris
Mouse
Mus musculus
Q80TL0
749
83400
S575
D
L
T
Q
I
E
A
S
K
P
H
S
T
Q
F
Rat
Rattus norvegicus
Q80Z30
750
83420
S575
D
L
T
Q
I
E
T
S
K
P
H
S
T
Q
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509388
612
67716
P451
E
A
S
G
P
G
G
P
E
G
A
V
W
A
D
Chicken
Gallus gallus
XP_415871
725
79898
S545
D
L
T
K
T
E
T
S
M
P
N
S
A
K
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001018354
633
71021
P469
P
L
Q
Q
C
S
A
P
A
D
L
A
Y
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202833
645
70404
A477
G
L
N
S
S
K
H
A
K
D
L
V
I
K
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.3
30.4
88.5
N.A.
88.3
87.7
N.A.
61.7
67.7
N.A.
42.4
N.A.
N.A.
N.A.
N.A.
27.9
Protein Similarity:
100
92.8
40.3
91.2
N.A.
91.9
90.7
N.A.
67
75.7
N.A.
55
N.A.
N.A.
N.A.
N.A.
43
P-Site Identity:
100
100
0
100
N.A.
93.3
86.6
N.A.
0
53.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
6.6
100
N.A.
93.3
86.6
N.A.
20
80
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
50
10
10
0
10
10
40
10
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
60
0
0
0
0
0
0
0
0
20
0
0
10
0
20
% D
% Glu:
10
0
0
0
10
60
0
0
10
10
0
0
0
20
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% F
% Gly:
10
0
0
10
0
10
10
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
20
0
0
0
50
0
0
0
0
% H
% Ile:
0
0
0
0
50
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
10
0
10
0
10
0
0
60
0
0
0
0
20
10
% K
% Leu:
0
80
10
0
0
0
0
0
0
0
20
0
0
0
0
% L
% Met:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
10
% N
% Pro:
10
0
0
0
10
10
0
20
10
60
0
0
0
0
0
% P
% Gln:
0
0
10
60
0
0
0
0
0
0
0
10
0
50
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% R
% Ser:
0
0
10
10
10
10
0
60
0
0
0
60
0
0
0
% S
% Thr:
0
0
60
0
10
0
20
0
0
0
0
0
20
0
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _