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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1E
All Species:
15.15
Human Site:
S670
Identified Species:
37.04
UniProt:
Q8WY54
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WY54
NP_055721.3
766
85242
S670
L
E
N
E
Q
F
K
S
P
G
N
R
V
S
R
Chimpanzee
Pan troglodytes
XP_523813
716
80142
S620
L
E
N
E
Q
F
K
S
P
G
N
R
V
S
R
Rhesus Macaque
Macaca mulatta
XP_001089477
455
49874
C360
E
D
Y
L
L
L
A
C
D
G
F
F
D
V
V
Dog
Lupus familis
XP_853253
755
84128
F658
L
E
D
E
Q
F
K
F
L
G
K
R
V
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q80TL0
749
83400
S654
L
E
N
E
Q
F
K
S
R
G
K
T
A
S
R
Rat
Rattus norvegicus
Q80Z30
750
83420
S655
L
E
N
E
Q
F
K
S
P
G
K
R
A
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509388
612
67716
R517
R
F
E
P
G
E
R
R
G
S
R
D
A
H
L
Chicken
Gallus gallus
XP_415871
725
79898
S628
L
E
D
E
L
F
K
S
L
G
K
Q
V
A
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001018354
633
71021
P538
R
P
Y
Q
E
D
D
P
S
G
Y
R
Q
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202833
645
70404
G544
R
S
S
L
N
K
K
G
S
S
P
I
R
R
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.3
30.4
88.5
N.A.
88.3
87.7
N.A.
61.7
67.7
N.A.
42.4
N.A.
N.A.
N.A.
N.A.
27.9
Protein Similarity:
100
92.8
40.3
91.2
N.A.
91.9
90.7
N.A.
67
75.7
N.A.
55
N.A.
N.A.
N.A.
N.A.
43
P-Site Identity:
100
100
6.6
73.3
N.A.
73.3
86.6
N.A.
0
53.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
13.3
80
N.A.
73.3
86.6
N.A.
6.6
73.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
0
0
0
30
10
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
10
20
0
0
10
10
0
10
0
0
10
10
0
0
% D
% Glu:
10
60
10
60
10
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
60
0
10
0
0
10
10
0
0
10
% F
% Gly:
0
0
0
0
10
0
0
10
10
80
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
0
10
70
0
0
0
40
0
0
10
0
% K
% Leu:
60
0
0
20
20
10
0
0
20
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
40
0
10
0
0
0
0
0
20
0
0
0
0
% N
% Pro:
0
10
0
10
0
0
0
10
30
0
10
0
0
0
10
% P
% Gln:
0
0
0
10
50
0
0
0
0
0
0
10
10
0
0
% Q
% Arg:
30
0
0
0
0
0
10
10
10
0
10
50
10
10
50
% R
% Ser:
0
10
10
0
0
0
0
50
20
20
0
0
0
50
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
40
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
20
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _