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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPM1E All Species: 16.97
Human Site: S714 Identified Species: 41.48
UniProt: Q8WY54 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WY54 NP_055721.3 766 85242 S714 P S H K I G T S L S S L T G S
Chimpanzee Pan troglodytes XP_523813 716 80142 S664 P S H K I G T S L S S L T G S
Rhesus Macaque Macaca mulatta XP_001089477 455 49874 H404 A A R E R G S H D N I T V M V
Dog Lupus familis XP_853253 755 84128 S702 P S H K I G T S L S S L I R S
Cat Felis silvestris
Mouse Mus musculus Q80TL0 749 83400 S698 P S H K I G I S L S S L T R S
Rat Rattus norvegicus Q80Z30 750 83420 S699 S S R K I G I S L S S L T R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509388 612 67716 P561 R A G T G R S P L V L A G R R
Chicken Gallus gallus XP_415871 725 79898 L672 S H R E G S G L P L P V R S R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001018354 633 71021 V582 R K K R R L D V L P L R R E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001202833 645 70404 S588 K K E K R D S S T K K S S P V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.3 30.4 88.5 N.A. 88.3 87.7 N.A. 61.7 67.7 N.A. 42.4 N.A. N.A. N.A. N.A. 27.9
Protein Similarity: 100 92.8 40.3 91.2 N.A. 91.9 90.7 N.A. 67 75.7 N.A. 55 N.A. N.A. N.A. N.A. 43
P-Site Identity: 100 100 6.6 86.6 N.A. 86.6 73.3 N.A. 6.6 0 N.A. 13.3 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 33.3 86.6 N.A. 86.6 73.3 N.A. 20 13.3 N.A. 20 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 20 0 0 0 0 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 10 0 10 0 0 0 0 0 0 % D
% Glu: 0 0 10 20 0 0 0 0 0 0 0 0 0 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 20 60 10 0 0 0 0 0 10 20 0 % G
% His: 0 10 40 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 50 0 20 0 0 0 10 0 10 0 0 % I
% Lys: 10 20 10 60 0 0 0 0 0 10 10 0 0 0 0 % K
% Leu: 0 0 0 0 0 10 0 10 70 10 20 50 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % N
% Pro: 40 0 0 0 0 0 0 10 10 10 10 0 0 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 20 0 30 10 30 10 0 0 0 0 0 10 20 40 20 % R
% Ser: 20 50 0 0 0 10 30 60 0 50 50 10 10 10 60 % S
% Thr: 0 0 0 10 0 0 30 0 10 0 0 10 40 0 0 % T
% Val: 0 0 0 0 0 0 0 10 0 10 0 10 10 0 20 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _