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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1E
All Species:
13.94
Human Site:
T719
Identified Species:
34.07
UniProt:
Q8WY54
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WY54
NP_055721.3
766
85242
T719
G
T
S
L
S
S
L
T
G
S
G
K
R
N
R
Chimpanzee
Pan troglodytes
XP_523813
716
80142
T669
G
T
S
L
S
S
L
T
G
S
G
K
R
N
R
Rhesus Macaque
Macaca mulatta
XP_001089477
455
49874
V409
G
S
H
D
N
I
T
V
M
V
V
F
L
R
D
Dog
Lupus familis
XP_853253
755
84128
I707
G
T
S
L
S
S
L
I
R
S
G
K
R
N
R
Cat
Felis silvestris
Mouse
Mus musculus
Q80TL0
749
83400
T703
G
I
S
L
S
S
L
T
R
S
G
K
R
N
K
Rat
Rattus norvegicus
Q80Z30
750
83420
T704
G
I
S
L
S
S
L
T
R
S
G
K
R
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509388
612
67716
G566
R
S
P
L
V
L
A
G
R
R
S
R
L
L
P
Chicken
Gallus gallus
XP_415871
725
79898
R677
S
G
L
P
L
P
V
R
S
R
G
S
T
R
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001018354
633
71021
R587
L
D
V
L
P
L
R
R
E
S
Q
R
L
T
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202833
645
70404
S593
D
S
S
T
K
K
S
S
P
V
Q
H
K
S
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.3
30.4
88.5
N.A.
88.3
87.7
N.A.
61.7
67.7
N.A.
42.4
N.A.
N.A.
N.A.
N.A.
27.9
Protein Similarity:
100
92.8
40.3
91.2
N.A.
91.9
90.7
N.A.
67
75.7
N.A.
55
N.A.
N.A.
N.A.
N.A.
43
P-Site Identity:
100
100
6.6
86.6
N.A.
80
80
N.A.
6.6
6.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
20
86.6
N.A.
86.6
86.6
N.A.
20
13.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
10
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
60
10
0
0
0
0
0
10
20
0
60
0
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
20
0
0
0
10
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
10
0
0
0
0
0
50
10
0
20
% K
% Leu:
10
0
10
70
10
20
50
0
0
0
0
0
30
10
10
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
50
0
% N
% Pro:
0
0
10
10
10
10
0
0
10
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% Q
% Arg:
10
0
0
0
0
0
10
20
40
20
0
20
50
20
40
% R
% Ser:
10
30
60
0
50
50
10
10
10
60
10
10
0
10
0
% S
% Thr:
0
30
0
10
0
0
10
40
0
0
0
0
10
10
0
% T
% Val:
0
0
10
0
10
0
10
10
0
20
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _