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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1E
All Species:
16.06
Human Site:
Y685
Identified Species:
39.26
UniProt:
Q8WY54
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WY54
NP_055721.3
766
85242
Y685
L
S
H
L
R
H
H
Y
S
K
K
W
H
R
F
Chimpanzee
Pan troglodytes
XP_523813
716
80142
Y635
L
S
H
L
H
H
H
Y
S
K
K
W
H
R
F
Rhesus Macaque
Macaca mulatta
XP_001089477
455
49874
L375
P
H
Q
E
V
V
G
L
V
Q
S
H
L
M
R
Dog
Lupus familis
XP_853253
755
84128
Y673
L
S
H
L
R
Y
H
Y
S
K
R
W
H
G
F
Cat
Felis silvestris
Mouse
Mus musculus
Q80TL0
749
83400
Y669
L
Y
H
L
R
H
H
Y
S
K
R
Q
R
G
F
Rat
Rattus norvegicus
Q80Z30
750
83420
Y670
L
Y
H
L
R
H
H
Y
S
K
R
Q
R
G
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509388
612
67716
R532
R
H
Y
D
Y
A
R
R
R
H
G
F
R
V
K
Chicken
Gallus gallus
XP_415871
725
79898
G643
F
H
F
R
F
C
N
G
K
R
R
R
G
A
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001018354
633
71021
S553
Q
P
N
P
R
V
P
S
Y
M
Q
T
T
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202833
645
70404
Q559
S
S
T
P
S
P
R
Q
K
K
P
S
Y
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.3
30.4
88.5
N.A.
88.3
87.7
N.A.
61.7
67.7
N.A.
42.4
N.A.
N.A.
N.A.
N.A.
27.9
Protein Similarity:
100
92.8
40.3
91.2
N.A.
91.9
90.7
N.A.
67
75.7
N.A.
55
N.A.
N.A.
N.A.
N.A.
43
P-Site Identity:
100
93.3
0
80
N.A.
66.6
66.6
N.A.
0
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
93.3
6.6
93.3
N.A.
73.3
73.3
N.A.
13.3
20
N.A.
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
10
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
10
0
10
0
10
0
0
0
0
0
0
10
0
0
50
% F
% Gly:
0
0
0
0
0
0
10
10
0
0
10
0
10
30
10
% G
% His:
0
30
50
0
10
40
50
0
0
10
0
10
30
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
20
60
20
0
0
0
10
% K
% Leu:
50
0
0
50
0
0
0
10
0
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% M
% Asn:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
10
10
0
20
0
10
10
0
0
0
10
0
0
0
0
% P
% Gln:
10
0
10
0
0
0
0
10
0
10
10
20
0
0
0
% Q
% Arg:
10
0
0
10
50
0
20
10
10
10
40
10
30
20
20
% R
% Ser:
10
40
0
0
10
0
0
10
50
0
10
10
0
10
0
% S
% Thr:
0
0
10
0
0
0
0
0
0
0
0
10
10
0
0
% T
% Val:
0
0
0
0
10
20
0
0
10
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
30
0
0
0
% W
% Tyr:
0
20
10
0
10
10
0
50
10
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _