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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYLIP
All Species:
22.42
Human Site:
S217
Identified Species:
44.85
UniProt:
Q8WY64
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WY64
NP_037394.2
445
49910
S217
S
I
C
K
D
D
F
S
P
I
N
R
I
A
Y
Chimpanzee
Pan troglodytes
XP_518252
445
49865
S217
S
I
C
K
D
D
F
S
P
I
N
R
I
A
Y
Rhesus Macaque
Macaca mulatta
XP_001094408
445
49830
S217
S
I
C
K
D
D
F
S
P
I
N
R
I
A
Y
Dog
Lupus familis
XP_545352
479
53801
C195
S
I
C
K
D
D
F
C
P
I
N
R
I
A
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8BM54
445
49831
S217
S
I
C
K
E
D
F
S
P
I
N
R
I
A
Y
Rat
Rattus norvegicus
B2RYE5
527
59553
K304
L
I
F
E
G
A
N
K
I
G
L
F
F
W
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520686
416
46554
S188
S
I
C
K
D
D
F
S
P
I
N
R
I
A
Y
Chicken
Gallus gallus
Q9PU45
583
68536
K233
N
I
Y
E
H
D
D
K
L
T
P
K
I
G
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6TEM9
472
53415
S217
A
I
C
R
D
D
F
S
L
V
N
R
I
S
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611680
676
73164
G357
G
I
T
V
C
R
G
G
E
K
Q
S
I
P
F
Honey Bee
Apis mellifera
XP_396349
451
51345
E200
T
V
Y
R
N
R
D
E
E
T
Q
N
I
P
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790458
429
48689
G211
E
V
G
V
G
A
H
G
I
L
V
T
N
I
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.8
84.1
N.A.
96.1
21.4
N.A.
84.7
22.2
N.A.
72.4
N.A.
26.3
38.1
N.A.
33
Protein Similarity:
100
100
99.3
85.8
N.A.
98.6
36.8
N.A.
88.3
39.1
N.A.
84.7
N.A.
39.7
53.8
N.A.
53.4
P-Site Identity:
100
100
100
93.3
N.A.
93.3
6.6
N.A.
100
20
N.A.
66.6
N.A.
13.3
13.3
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
100
13.3
N.A.
100
46.6
N.A.
93.3
N.A.
20
40
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
17
0
0
0
0
0
0
0
50
0
% A
% Cys:
0
0
59
0
9
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
50
67
17
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
0
17
9
0
0
9
17
0
0
0
0
0
9
% E
% Phe:
0
0
9
0
0
0
59
0
0
0
0
9
9
0
17
% F
% Gly:
9
0
9
0
17
0
9
17
0
9
0
0
0
9
0
% G
% His:
0
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
84
0
0
0
0
0
0
17
50
0
0
84
9
0
% I
% Lys:
0
0
0
50
0
0
0
17
0
9
0
9
0
0
0
% K
% Leu:
9
0
0
0
0
0
0
0
17
9
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
9
0
9
0
0
0
59
9
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
50
0
9
0
0
17
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% Q
% Arg:
0
0
0
17
0
17
0
0
0
0
0
59
0
0
0
% R
% Ser:
50
0
0
0
0
0
0
50
0
0
0
9
0
9
0
% S
% Thr:
9
0
9
0
0
0
0
0
0
17
0
9
0
0
0
% T
% Val:
0
17
0
17
0
0
0
0
0
9
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
67
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _