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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYLIP All Species: 20.3
Human Site: S345 Identified Species: 40.61
UniProt: Q8WY64 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WY64 NP_037394.2 445 49910 S345 L V S R N N Q S P S H S P L K
Chimpanzee Pan troglodytes XP_518252 445 49865 S345 L V S R S N Q S P S H S P L K
Rhesus Macaque Macaca mulatta XP_001094408 445 49830 S345 L V S R S N Q S P S H S P L K
Dog Lupus familis XP_545352 479 53801 S323 L V S R S D H S P P N S P L K
Cat Felis silvestris
Mouse Mus musculus Q8BM54 445 49831 S345 L V S R S D Q S P P S S P L K
Rat Rattus norvegicus B2RYE5 527 59553 I432 F K A S N P V I A A Q L C S K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520686 416 46554 S316 L V P R R G P S P P S S P L K
Chicken Gallus gallus Q9PU45 583 68536 A361 I E E Q T M K A Q K E L E E Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6TEM9 472 53415 R345 M M S R P G E R T P S N R S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611680 676 73164 S485 A E G A E G C S A V A G G L G
Honey Bee Apis mellifera XP_396349 451 51345 L328 L P E E K E I L E K H D C G D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790458 429 48689 G339 R R K L F R M G I S T Q S A D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 98.8 84.1 N.A. 96.1 21.4 N.A. 84.7 22.2 N.A. 72.4 N.A. 26.3 38.1 N.A. 33
Protein Similarity: 100 100 99.3 85.8 N.A. 98.6 36.8 N.A. 88.3 39.1 N.A. 84.7 N.A. 39.7 53.8 N.A. 53.4
P-Site Identity: 100 93.3 93.3 66.6 N.A. 73.3 13.3 N.A. 60 0 N.A. 13.3 N.A. 13.3 13.3 N.A. 6.6
P-Site Similarity: 100 100 100 86.6 N.A. 86.6 26.6 N.A. 60 33.3 N.A. 40 N.A. 13.3 13.3 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 9 0 0 0 9 17 9 9 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 0 0 17 0 0 % C
% Asp: 0 0 0 0 0 17 0 0 0 0 0 9 0 0 17 % D
% Glu: 0 17 17 9 9 9 9 0 9 0 9 0 9 9 0 % E
% Phe: 9 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 0 0 25 0 9 0 0 0 9 9 9 9 % G
% His: 0 0 0 0 0 0 9 0 0 0 34 0 0 0 0 % H
% Ile: 9 0 0 0 0 0 9 9 9 0 0 0 0 0 0 % I
% Lys: 0 9 9 0 9 0 9 0 0 17 0 0 0 0 59 % K
% Leu: 59 0 0 9 0 0 0 9 0 0 0 17 0 59 0 % L
% Met: 9 9 0 0 0 9 9 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 17 25 0 0 0 0 9 9 0 0 0 % N
% Pro: 0 9 9 0 9 9 9 0 50 34 0 0 50 0 9 % P
% Gln: 0 0 0 9 0 0 34 0 9 0 9 9 0 0 9 % Q
% Arg: 9 9 0 59 9 9 0 9 0 0 0 0 9 0 0 % R
% Ser: 0 0 50 9 34 0 0 59 0 34 25 50 9 17 0 % S
% Thr: 0 0 0 0 9 0 0 0 9 0 9 0 0 0 0 % T
% Val: 0 50 0 0 0 0 9 0 0 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _