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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYLIP All Species: 20
Human Site: S349 Identified Species: 40
UniProt: Q8WY64 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WY64 NP_037394.2 445 49910 S349 N N Q S P S H S P L K S S E S
Chimpanzee Pan troglodytes XP_518252 445 49865 S349 S N Q S P S H S P L K S S E S
Rhesus Macaque Macaca mulatta XP_001094408 445 49830 S349 S N Q S P S H S P L K S S E S
Dog Lupus familis XP_545352 479 53801 S327 S D H S P P N S P L K S S E S
Cat Felis silvestris
Mouse Mus musculus Q8BM54 445 49831 S349 S D Q S P P S S P L K S S D S
Rat Rattus norvegicus B2RYE5 527 59553 L436 N P V I A A Q L C S K T N P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520686 416 46554 S320 R G P S P P S S P L K S S E N
Chicken Gallus gallus Q9PU45 583 68536 L365 T M K A Q K E L E E Q T R R A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6TEM9 472 53415 N349 P G E R T P S N R S P S R E Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611680 676 73164 G489 E G C S A V A G G L G A S A V
Honey Bee Apis mellifera XP_396349 451 51345 D332 K E I L E K H D C G D C E E P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790458 429 48689 Q343 F R M G I S T Q S A D A D L S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 98.8 84.1 N.A. 96.1 21.4 N.A. 84.7 22.2 N.A. 72.4 N.A. 26.3 38.1 N.A. 33
Protein Similarity: 100 100 99.3 85.8 N.A. 98.6 36.8 N.A. 88.3 39.1 N.A. 84.7 N.A. 39.7 53.8 N.A. 53.4
P-Site Identity: 100 93.3 93.3 66.6 N.A. 66.6 13.3 N.A. 60 0 N.A. 13.3 N.A. 20 13.3 N.A. 13.3
P-Site Similarity: 100 100 100 86.6 N.A. 86.6 33.3 N.A. 66.6 33.3 N.A. 26.6 N.A. 26.6 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 17 9 9 0 0 9 0 17 0 9 9 % A
% Cys: 0 0 9 0 0 0 0 0 17 0 0 9 0 0 0 % C
% Asp: 0 17 0 0 0 0 0 9 0 0 17 0 9 9 0 % D
% Glu: 9 9 9 0 9 0 9 0 9 9 0 0 9 59 9 % E
% Phe: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 25 0 9 0 0 0 9 9 9 9 0 0 0 0 % G
% His: 0 0 9 0 0 0 34 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 9 9 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 0 9 0 0 17 0 0 0 0 59 0 0 0 0 % K
% Leu: 0 0 0 9 0 0 0 17 0 59 0 0 0 9 0 % L
% Met: 0 9 9 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 17 25 0 0 0 0 9 9 0 0 0 0 9 0 9 % N
% Pro: 9 9 9 0 50 34 0 0 50 0 9 0 0 9 9 % P
% Gln: 0 0 34 0 9 0 9 9 0 0 9 0 0 0 9 % Q
% Arg: 9 9 0 9 0 0 0 0 9 0 0 0 17 9 0 % R
% Ser: 34 0 0 59 0 34 25 50 9 17 0 59 59 0 50 % S
% Thr: 9 0 0 0 9 0 9 0 0 0 0 17 0 0 0 % T
% Val: 0 0 9 0 0 9 0 0 0 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _