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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYLIP All Species: 19.7
Human Site: S357 Identified Species: 39.39
UniProt: Q8WY64 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WY64 NP_037394.2 445 49910 S357 P L K S S E S S M N C S S C E
Chimpanzee Pan troglodytes XP_518252 445 49865 S357 P L K S S E S S M N C S S C E
Rhesus Macaque Macaca mulatta XP_001094408 445 49830 S357 P L K S S E S S M N C S S C E
Dog Lupus familis XP_545352 479 53801 S335 P L K S S E S S M N C T S C E
Cat Felis silvestris
Mouse Mus musculus Q8BM54 445 49831 S357 P L K S S D S S M S C S S C E
Rat Rattus norvegicus B2RYE5 527 59553 V444 C S K T N P E V H N Y Q P Q F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520686 416 46554 G328 P L K S S E N G R N C G S C E
Chicken Gallus gallus Q9PU45 583 68536 L373 E E Q T R R A L E L D Q E R K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6TEM9 472 53415 E357 R S P S R E Q E G A L D C G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611680 676 73164 G497 G L G A S A V G E P G V S P W
Honey Bee Apis mellifera XP_396349 451 51345 K340 C G D C E E P K C K E S R E C
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790458 429 48689 S351 S A D A D L S S Q A H N R Q E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 98.8 84.1 N.A. 96.1 21.4 N.A. 84.7 22.2 N.A. 72.4 N.A. 26.3 38.1 N.A. 33
Protein Similarity: 100 100 99.3 85.8 N.A. 98.6 36.8 N.A. 88.3 39.1 N.A. 84.7 N.A. 39.7 53.8 N.A. 53.4
P-Site Identity: 100 100 100 93.3 N.A. 86.6 13.3 N.A. 73.3 0 N.A. 13.3 N.A. 20 13.3 N.A. 20
P-Site Similarity: 100 100 100 100 N.A. 100 26.6 N.A. 80 26.6 N.A. 13.3 N.A. 26.6 13.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 17 0 9 9 0 0 17 0 0 0 0 0 % A
% Cys: 17 0 0 9 0 0 0 0 9 0 50 0 9 50 9 % C
% Asp: 0 0 17 0 9 9 0 0 0 0 9 9 0 0 0 % D
% Glu: 9 9 0 0 9 59 9 9 17 0 9 0 9 9 59 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % F
% Gly: 9 9 9 0 0 0 0 17 9 0 9 9 0 9 9 % G
% His: 0 0 0 0 0 0 0 0 9 0 9 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 59 0 0 0 0 9 0 9 0 0 0 0 9 % K
% Leu: 0 59 0 0 0 9 0 9 0 9 9 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 42 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 9 0 0 50 0 9 0 0 0 % N
% Pro: 50 0 9 0 0 9 9 0 0 9 0 0 9 9 0 % P
% Gln: 0 0 9 0 0 0 9 0 9 0 0 17 0 17 0 % Q
% Arg: 9 0 0 0 17 9 0 0 9 0 0 0 17 9 0 % R
% Ser: 9 17 0 59 59 0 50 50 0 9 0 42 59 0 0 % S
% Thr: 0 0 0 17 0 0 0 0 0 0 0 9 0 0 0 % T
% Val: 0 0 0 0 0 0 9 9 0 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _