KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTNNBL1
All Species:
9.09
Human Site:
T477
Identified Species:
18.18
UniProt:
Q8WYA6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WYA6
NP_110517.2
563
65173
T477
G
E
I
I
D
N
D
T
E
E
E
F
Y
L
R
Chimpanzee
Pan troglodytes
XP_001142442
586
67977
T500
G
E
I
I
D
N
D
T
E
E
E
F
Y
L
R
Rhesus Macaque
Macaca mulatta
XP_001091478
563
65153
I477
G
E
I
I
D
N
D
I
E
E
E
F
Y
L
R
Dog
Lupus familis
XP_534415
563
65192
T477
G
E
I
I
D
N
D
T
E
D
E
F
Y
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWL8
563
64962
M477
G
E
I
I
D
N
D
M
E
D
E
F
Y
L
R
Rat
Rattus norvegicus
Q4V8K2
563
64930
M477
G
E
I
I
D
N
D
M
E
D
E
F
Y
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234108
563
65135
M477
G
E
I
I
D
D
D
M
E
D
E
F
Y
L
R
Frog
Xenopus laevis
NP_001087114
555
63993
L469
G
E
I
L
D
D
D
L
E
E
E
F
Y
L
R
Zebra Danio
Brachydanio rerio
NP_957160
563
64365
M477
G
E
I
L
D
D
A
M
D
D
E
F
Y
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649847
581
66065
E497
P
T
I
D
E
D
E
E
A
E
N
N
Y
I
K
Honey Bee
Apis mellifera
XP_393169
578
66598
D492
K
N
T
K
E
D
E
D
E
E
E
S
Y
L
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786059
560
63361
Q473
G
D
I
I
D
D
D
Q
E
D
E
Y
Y
I
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.2
99.6
98.4
N.A.
96
96.8
N.A.
N.A.
92.9
80.4
78.6
N.A.
55.9
61.9
N.A.
59.6
Protein Similarity:
100
95.9
99.8
99.1
N.A.
97.5
98.2
N.A.
N.A.
96.9
90.2
91.6
N.A.
73.1
77.6
N.A.
76.7
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
86.6
N.A.
N.A.
80
80
60
N.A.
20
40
N.A.
53.3
P-Site Similarity:
100
100
93.3
100
N.A.
93.3
93.3
N.A.
N.A.
93.3
93.3
86.6
N.A.
53.3
60
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
9
84
50
75
9
9
50
0
0
0
0
0
% D
% Glu:
0
75
0
0
17
0
17
9
84
50
92
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
75
0
0
0
% F
% Gly:
84
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
92
67
0
0
0
9
0
0
0
0
0
17
0
% I
% Lys:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% K
% Leu:
0
0
0
17
0
0
0
9
0
0
0
0
0
84
0
% L
% Met:
0
0
0
0
0
0
0
34
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
50
0
0
0
0
9
9
0
0
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
84
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% S
% Thr:
0
9
9
0
0
0
0
25
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
9
100
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _