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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYST4 All Species: 27.27
Human Site: S217 Identified Species: 66.67
UniProt: Q8WYB5 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WYB5 NP_036462.2 2073 231378 S217 A D P I P I C S F C L G T K E
Chimpanzee Pan troglodytes XP_519734 1952 219524 S210 A E P I P I C S F C L G T K E
Rhesus Macaque Macaca mulatta XP_001094798 1531 171769
Dog Lupus familis XP_536397 2090 233726 S217 A D P I P I C S F C L G T K E
Cat Felis silvestris
Mouse Mus musculus Q8BRB7 1872 208521 R159 R L R L G A K R A V N N G R L
Rat Rattus norvegicus Q5TKR9 1998 223312 S210 A E P I P I C S F C L G T K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506182 2088 231546 S217 A D P I P I C S F C L G T K E
Chicken Gallus gallus XP_421609 2013 224707 S217 A D P I P I C S F C L G T K E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_697383 2011 222731 S217 A D P I P I C S F C L G T K E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786050 3082 341137 R211 A E P I L V C R S C H G T A E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 45.2 33.1 94.2 N.A. 82.6 43.8 N.A. 83.6 81.4 N.A. 56.9 N.A. N.A. N.A. N.A. 27.3
Protein Similarity: 100 59.1 46.7 96.1 N.A. 86 58.3 N.A. 89.5 87.9 N.A. 70 N.A. N.A. N.A. N.A. 40.6
P-Site Identity: 100 93.3 0 100 N.A. 0 93.3 N.A. 100 100 N.A. 100 N.A. N.A. N.A. N.A. 53.3
P-Site Similarity: 100 100 0 100 N.A. 13.3 100 N.A. 100 100 N.A. 100 N.A. N.A. N.A. N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 80 0 0 0 0 10 0 0 10 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 80 0 0 80 0 0 0 0 0 % C
% Asp: 0 50 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 30 0 0 0 0 0 0 0 0 0 0 0 0 80 % E
% Phe: 0 0 0 0 0 0 0 0 70 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 0 0 0 0 0 0 80 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 0 0 0 80 0 70 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 10 0 0 0 0 0 0 70 0 % K
% Leu: 0 10 0 10 10 0 0 0 0 0 70 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % N
% Pro: 0 0 80 0 70 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 0 10 0 0 0 0 20 0 0 0 0 0 10 0 % R
% Ser: 0 0 0 0 0 0 0 70 10 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 80 0 0 % T
% Val: 0 0 0 0 0 10 0 0 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _