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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACOT12
All Species:
28.18
Human Site:
S408
Identified Species:
68.89
UniProt:
Q8WYK0
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WYK0
NP_570123.1
555
62034
S408
H
L
A
Y
R
L
L
S
D
F
T
K
R
P
L
Chimpanzee
Pan troglodytes
XP_517670
555
62009
S408
H
L
A
Y
H
L
L
S
D
F
T
K
R
P
L
Rhesus Macaque
Macaca mulatta
XP_001111108
555
61914
S408
H
L
A
Y
R
L
L
S
D
F
T
K
R
P
L
Dog
Lupus familis
XP_546042
553
61462
S406
H
L
T
Y
H
L
L
S
D
F
T
K
R
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBK0
556
61743
S409
H
I
A
Y
H
L
L
S
D
L
T
K
R
P
L
Rat
Rattus norvegicus
Q99NB7
556
61999
S409
R
V
A
Y
H
L
L
S
D
F
T
K
R
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512077
501
55911
F356
V
F
S
V
L
S
D
F
T
K
R
P
Q
W
D
Chicken
Gallus gallus
XP_426664
1004
109343
S854
S
Q
A
F
S
L
L
S
D
L
R
R
R
H
E
Frog
Xenopus laevis
NP_001086106
577
64832
S432
Q
Q
A
Y
F
L
L
S
D
L
G
L
R
P
N
Zebra Danio
Brachydanio rerio
NP_001093445
577
65213
S425
Q
R
A
F
T
L
L
S
D
L
S
R
R
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97.6
85.7
N.A.
81.2
78.5
N.A.
65.2
26.5
55.9
48.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
99.2
91.8
N.A.
90.2
88.6
N.A.
74.5
36.3
70
63.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
86.6
N.A.
80
80
N.A.
0
40
53.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
86.6
N.A.
86.6
86.6
N.A.
13.3
53.3
53.3
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
80
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
90
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% E
% Phe:
0
10
0
20
10
0
0
10
0
50
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% G
% His:
50
0
0
0
40
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
0
60
0
0
0
% K
% Leu:
0
40
0
0
10
90
90
0
0
40
0
10
0
0
60
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
0
70
0
% P
% Gln:
20
20
0
0
0
0
0
0
0
0
0
0
10
10
0
% Q
% Arg:
10
10
0
0
20
0
0
0
0
0
20
20
90
0
0
% R
% Ser:
10
0
10
0
10
10
0
90
0
0
10
0
0
0
0
% S
% Thr:
0
0
10
0
10
0
0
0
10
0
60
0
0
0
0
% T
% Val:
10
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
70
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _