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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SSH1
All Species:
23.94
Human Site:
S333
Identified Species:
43.89
UniProt:
Q8WYL5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WYL5
NP_001154802.1
1049
115511
S333
N
L
E
E
L
Q
G
S
G
V
D
Y
I
L
N
Chimpanzee
Pan troglodytes
XP_522524
1056
116594
S333
N
L
E
E
L
Q
G
S
G
V
D
Y
I
L
N
Rhesus Macaque
Macaca mulatta
XP_001096246
1148
127068
S431
N
L
E
E
L
Q
G
S
G
V
D
Y
I
L
N
Dog
Lupus familis
XP_851712
1056
116328
S333
N
L
E
E
L
Q
G
S
G
V
D
Y
I
L
N
Cat
Felis silvestris
Mouse
Mus musculus
Q76I79
1042
115278
S333
N
L
E
E
L
Q
G
S
G
V
D
Y
I
L
N
Rat
Rattus norvegicus
Q5XIS1
652
72053
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510076
1531
167423
R482
N
L
E
D
L
Q
N
R
G
V
R
Y
I
L
N
Chicken
Gallus gallus
XP_425274
1087
121313
S340
N
L
E
E
L
Q
G
S
G
I
D
Y
I
L
N
Frog
Xenopus laevis
Q6IVY4
691
78886
G14
Q
V
S
S
L
D
V
G
S
N
I
T
P
V
Q
Zebra Danio
Brachydanio rerio
XP_695867
962
107543
N286
L
E
Q
H
M
S
C
N
L
R
E
Y
K
E
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q6NN85
1045
114979
T326
K
P
P
E
K
E
E
T
E
S
V
I
K
M
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10038
657
70984
Sea Urchin
Strong. purpuratus
XP_001189133
1261
140489
N475
D
L
D
E
L
E
E
N
G
V
G
Y
I
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92
86.5
85.2
N.A.
82.3
32
N.A.
34.5
67.1
32.1
48.1
N.A.
33.2
N.A.
21.9
28
Protein Similarity:
100
93.5
88.1
89
N.A.
87.3
43.8
N.A.
44.9
75.8
45
60.2
N.A.
49
N.A.
35.5
43.4
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
73.3
93.3
6.6
6.6
N.A.
6.6
N.A.
0
60
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
80
100
20
33.3
N.A.
26.6
N.A.
0
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
8
0
8
0
0
0
0
47
0
0
0
0
% D
% Glu:
0
8
54
62
0
16
16
0
8
0
8
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
47
8
62
0
8
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
8
8
62
0
0
% I
% Lys:
8
0
0
0
8
0
0
0
0
0
0
0
16
0
8
% K
% Leu:
8
62
0
0
70
0
0
0
8
0
0
0
0
62
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
54
0
0
0
0
0
8
16
0
8
0
0
0
0
62
% N
% Pro:
0
8
8
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
8
0
8
0
0
54
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
8
0
8
8
0
0
0
0
% R
% Ser:
0
0
8
8
0
8
0
47
8
8
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% T
% Val:
0
8
0
0
0
0
8
0
0
54
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
70
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _