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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SSH1 All Species: 14.24
Human Site: T725 Identified Species: 26.11
UniProt: Q8WYL5 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WYL5 NP_001154802.1 1049 115511 T725 A G S R R A D T S G P G A G A
Chimpanzee Pan troglodytes XP_522524 1056 116594 T732 A G S R R A D T S G P G A G A
Rhesus Macaque Macaca mulatta XP_001096246 1148 127068 T824 A G S R R P D T S V P G A G A
Dog Lupus familis XP_851712 1056 116328 T733 A G S R R S D T G G S G A A A
Cat Felis silvestris
Mouse Mus musculus Q76I79 1042 115278 G710 A P E R P A S G P A N T S P F
Rat Rattus norvegicus Q5XIS1 652 72053 F330 Q D R A S R I F P H L Y L G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510076 1531 167423 P1033 R K N S K N D P A P A E T T P
Chicken Gallus gallus XP_425274 1087 121313 L758 L S A G G G V L E A G T C K S
Frog Xenopus laevis Q6IVY4 691 78886 A369 T H A F I T T A R H Q G S R V
Zebra Danio Brachydanio rerio XP_695867 962 107543 A641 N R F N N E N A N N S N R L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q6NN85 1045 114979 T696 T S L T K L I T Q T S H L G K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10038 657 70984 Y336 R P H R H M D Y Y G P S D L C
Sea Urchin Strong. purpuratus XP_001189133 1261 140489 V886 E T Q V V S I V D E L A S S A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92 86.5 85.2 N.A. 82.3 32 N.A. 34.5 67.1 32.1 48.1 N.A. 33.2 N.A. 21.9 28
Protein Similarity: 100 93.5 88.1 89 N.A. 87.3 43.8 N.A. 44.9 75.8 45 60.2 N.A. 49 N.A. 35.5 43.4
P-Site Identity: 100 100 86.6 73.3 N.A. 20 6.6 N.A. 6.6 0 6.6 6.6 N.A. 13.3 N.A. 26.6 6.6
P-Site Similarity: 100 100 86.6 80 N.A. 26.6 13.3 N.A. 26.6 13.3 20 20 N.A. 20 N.A. 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 39 0 16 8 0 24 0 16 8 16 8 8 31 8 47 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % C
% Asp: 0 8 0 0 0 0 47 0 8 0 0 0 8 0 0 % D
% Glu: 8 0 8 0 0 8 0 0 8 8 0 8 0 0 0 % E
% Phe: 0 0 8 8 0 0 0 8 0 0 0 0 0 0 8 % F
% Gly: 0 31 0 8 8 8 0 8 8 31 8 39 0 39 0 % G
% His: 0 8 8 0 8 0 0 0 0 16 0 8 0 0 0 % H
% Ile: 0 0 0 0 8 0 24 0 0 0 0 0 0 0 0 % I
% Lys: 0 8 0 0 16 0 0 0 0 0 0 0 0 8 8 % K
% Leu: 8 0 8 0 0 8 0 8 0 0 16 0 16 16 0 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 8 8 8 8 8 0 8 8 8 8 0 0 0 % N
% Pro: 0 16 0 0 8 8 0 8 16 8 31 0 0 8 8 % P
% Gln: 8 0 8 0 0 0 0 0 8 0 8 0 0 0 0 % Q
% Arg: 16 8 8 47 31 8 0 0 8 0 0 0 8 8 0 % R
% Ser: 0 16 31 8 8 16 8 0 24 0 24 8 24 8 16 % S
% Thr: 16 8 0 8 0 8 8 39 0 8 0 16 8 8 0 % T
% Val: 0 0 0 8 8 0 8 8 0 8 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 8 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _