KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SSH1
All Species:
33.94
Human Site:
Y407
Identified Species:
62.22
UniProt:
Q8WYL5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WYL5
NP_001154802.1
1049
115511
Y407
S
A
S
T
V
I
A
Y
A
M
K
E
F
G
W
Chimpanzee
Pan troglodytes
XP_522524
1056
116594
Y407
S
A
S
T
V
I
A
Y
A
M
K
E
F
G
W
Rhesus Macaque
Macaca mulatta
XP_001096246
1148
127068
Y505
S
A
S
T
V
I
A
Y
A
M
K
E
F
G
W
Dog
Lupus familis
XP_851712
1056
116328
Y407
S
A
S
T
V
I
A
Y
A
M
K
E
F
G
W
Cat
Felis silvestris
Mouse
Mus musculus
Q76I79
1042
115278
Y407
S
A
S
T
V
I
A
Y
A
M
K
E
F
G
W
Rat
Rattus norvegicus
Q5XIS1
652
72053
Q49
R
G
A
V
L
G
L
Q
D
G
G
E
G
N
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510076
1531
167423
Y556
S
A
S
T
V
I
A
Y
A
M
K
E
Y
G
W
Chicken
Gallus gallus
XP_425274
1087
121313
Y414
S
A
S
T
V
I
A
Y
A
M
K
E
F
G
W
Frog
Xenopus laevis
Q6IVY4
691
78886
A88
E
E
D
T
L
T
L
A
V
R
L
E
P
V
R
Zebra Danio
Brachydanio rerio
XP_695867
962
107543
Y360
C
Y
C
N
V
R
V
Y
D
D
E
T
T
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q6NN85
1045
114979
S400
L
G
S
E
W
N
A
S
N
L
E
E
L
Q
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10038
657
70984
R55
F
F
S
K
L
I
R
R
R
L
F
E
N
K
L
Sea Urchin
Strong. purpuratus
XP_001189133
1261
140489
Y549
S
A
S
T
V
I
A
Y
A
M
K
E
Y
G
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92
86.5
85.2
N.A.
82.3
32
N.A.
34.5
67.1
32.1
48.1
N.A.
33.2
N.A.
21.9
28
Protein Similarity:
100
93.5
88.1
89
N.A.
87.3
43.8
N.A.
44.9
75.8
45
60.2
N.A.
49
N.A.
35.5
43.4
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
93.3
100
13.3
13.3
N.A.
20
N.A.
20
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
100
100
20
20
N.A.
33.3
N.A.
33.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
62
8
0
0
0
70
8
62
0
0
0
0
0
0
% A
% Cys:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
16
8
0
0
0
8
8
% D
% Glu:
8
8
0
8
0
0
0
0
0
0
16
93
0
0
0
% E
% Phe:
8
8
0
0
0
0
0
0
0
0
8
0
47
0
0
% F
% Gly:
0
16
0
0
0
8
0
0
0
8
8
0
8
62
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
70
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
62
0
0
8
8
% K
% Leu:
8
0
0
0
24
0
16
0
0
16
8
0
8
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
62
0
0
0
0
8
% M
% Asn:
0
0
0
8
0
8
0
0
8
0
0
0
8
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% Q
% Arg:
8
0
0
0
0
8
8
8
8
8
0
0
0
0
8
% R
% Ser:
62
0
77
0
0
0
0
8
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
70
0
8
0
0
0
0
0
8
8
0
0
% T
% Val:
0
0
0
8
70
0
8
0
8
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
54
% W
% Tyr:
0
8
0
0
0
0
0
70
0
0
0
0
16
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _