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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4A
All Species:
15.76
Human Site:
S207
Identified Species:
31.52
UniProt:
Q8WYN0
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WYN0
NP_443168.2
398
45378
S207
P
P
D
S
L
T
A
S
N
Q
S
K
G
T
S
Chimpanzee
Pan troglodytes
XP_529098
398
45427
S207
P
P
D
S
L
T
A
S
N
Q
S
K
G
T
S
Rhesus Macaque
Macaca mulatta
XP_001097251
398
45435
S207
P
L
D
Y
L
T
A
S
N
Q
S
K
G
T
S
Dog
Lupus familis
XP_538136
460
52068
S269
P
L
N
T
L
N
A
S
N
Q
S
K
S
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8C9S8
396
45076
R208
L
T
A
S
N
Q
S
R
D
T
S
V
P
C
S
Rat
Rattus norvegicus
NP_001119770
406
45887
S208
P
P
D
S
L
I
A
S
S
Q
S
K
G
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513122
528
59425
F341
S
E
F
L
L
N
G
F
P
S
G
A
E
V
T
Chicken
Gallus gallus
Q5ZIW7
380
43364
N193
H
R
S
A
L
G
R
N
R
N
A
A
G
L
C
Frog
Xenopus laevis
Q6GPU1
397
45280
R209
S
H
Q
S
T
W
S
R
C
R
D
T
S
G
H
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
C211
N
G
D
L
E
G
A
C
A
L
A
E
E
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198708
393
44309
A218
T
N
G
L
M
E
G
A
C
V
S
P
G
G
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
H221
E
P
S
A
F
S
I
H
N
L
I
I
A
G
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.7
81.5
N.A.
91.9
91.3
N.A.
41.4
78.6
74.3
54.5
N.A.
N.A.
N.A.
N.A.
47.2
Protein Similarity:
100
99.5
99.2
83.9
N.A.
95.7
95.5
N.A.
55.8
86.1
84.9
70.5
N.A.
N.A.
N.A.
N.A.
64.5
P-Site Identity:
100
100
86.6
53.3
N.A.
20
86.6
N.A.
6.6
13.3
6.6
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
86.6
66.6
N.A.
33.3
93.3
N.A.
13.3
33.3
20
33.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
17
0
0
50
9
9
0
17
17
9
9
9
% A
% Cys:
0
0
0
0
0
0
0
9
17
0
0
0
0
9
9
% C
% Asp:
0
0
42
0
0
0
0
0
9
0
9
0
0
0
0
% D
% Glu:
9
9
0
0
9
9
0
0
0
0
0
9
17
9
0
% E
% Phe:
0
0
9
0
9
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
9
9
0
0
17
17
0
0
0
9
0
50
25
0
% G
% His:
9
9
0
0
0
0
0
9
0
0
0
0
0
0
9
% H
% Ile:
0
0
0
0
0
9
9
0
0
0
9
9
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
42
0
0
0
% K
% Leu:
9
17
0
25
59
0
0
0
0
17
0
0
0
9
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
9
9
0
9
17
0
9
42
9
0
0
0
0
0
% N
% Pro:
42
34
0
0
0
0
0
0
9
0
0
9
9
0
9
% P
% Gln:
0
0
9
0
0
9
0
0
0
42
0
0
0
0
0
% Q
% Arg:
0
9
0
0
0
0
9
17
9
9
0
0
0
0
0
% R
% Ser:
17
0
17
42
0
9
17
42
9
9
59
0
17
0
42
% S
% Thr:
9
9
0
9
9
25
0
0
0
9
0
9
0
34
17
% T
% Val:
0
0
0
0
0
0
0
0
0
9
0
9
0
9
9
% V
% Trp:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _