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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4A
All Species:
28.18
Human Site:
Y170
Identified Species:
56.36
UniProt:
Q8WYN0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WYN0
NP_443168.2
398
45378
Y170
E
W
N
S
L
A
V
Y
V
S
M
D
N
T
V
Chimpanzee
Pan troglodytes
XP_529098
398
45427
Y170
E
W
N
S
L
A
V
Y
V
S
M
D
N
T
V
Rhesus Macaque
Macaca mulatta
XP_001097251
398
45435
Y170
E
W
N
S
L
A
V
Y
V
S
M
D
N
T
V
Dog
Lupus familis
XP_538136
460
52068
Y232
E
W
N
S
L
A
I
Y
V
S
M
D
N
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8C9S8
396
45076
Y170
E
W
N
S
L
A
V
Y
V
S
M
D
N
T
V
Rat
Rattus norvegicus
NP_001119770
406
45887
Y170
E
W
N
S
L
A
V
Y
V
S
M
D
N
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513122
528
59425
H303
T
W
S
S
L
A
V
H
I
A
M
D
N
T
V
Chicken
Gallus gallus
Q5ZIW7
380
43364
D157
L
A
V
Y
V
S
M
D
N
T
V
V
I
E
D
Frog
Xenopus laevis
Q6GPU1
397
45280
Y172
E
W
N
S
L
A
V
Y
V
S
M
D
N
T
V
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
H167
S
W
S
R
L
A
V
H
V
A
M
D
N
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198708
393
44309
H173
S
W
S
D
L
A
V
H
V
A
L
D
N
T
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
T163
P
F
R
D
T
T
Y
T
S
D
V
N
W
G
C
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.7
81.5
N.A.
91.9
91.3
N.A.
41.4
78.6
74.3
54.5
N.A.
N.A.
N.A.
N.A.
47.2
Protein Similarity:
100
99.5
99.2
83.9
N.A.
95.7
95.5
N.A.
55.8
86.1
84.9
70.5
N.A.
N.A.
N.A.
N.A.
64.5
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
66.6
0
100
66.6
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
33.3
100
86.6
N.A.
N.A.
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
84
0
0
0
25
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
0
17
0
0
0
9
0
9
0
84
0
0
9
% D
% Glu:
59
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
25
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
9
0
0
0
9
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
0
0
84
0
0
0
0
0
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
75
0
0
0
0
% M
% Asn:
0
0
59
0
0
0
0
0
9
0
0
9
84
0
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
17
0
25
67
0
9
0
0
9
59
0
0
0
0
0
% S
% Thr:
9
0
0
0
9
9
0
9
0
9
0
0
0
84
0
% T
% Val:
0
0
9
0
9
0
75
0
75
0
17
9
0
0
84
% V
% Trp:
0
84
0
0
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
0
0
0
9
0
0
9
59
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _