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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4A
All Species:
10.61
Human Site:
Y22
Identified Species:
21.21
UniProt:
Q8WYN0
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WYN0
NP_443168.2
398
45378
Y22
F
T
D
Y
L
E
E
Y
P
D
T
D
E
L
V
Chimpanzee
Pan troglodytes
XP_529098
398
45427
Y22
F
T
D
Y
L
E
E
Y
P
D
T
D
E
L
V
Rhesus Macaque
Macaca mulatta
XP_001097251
398
45435
Y22
F
T
D
Y
L
E
E
Y
P
D
T
D
E
L
V
Dog
Lupus familis
XP_538136
460
52068
F84
F
A
D
Y
L
E
E
F
P
D
S
D
E
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8C9S8
396
45076
F22
F
P
D
Y
L
E
E
F
P
D
T
D
E
L
V
Rat
Rattus norvegicus
NP_001119770
406
45887
F22
F
T
E
Y
L
E
E
F
P
D
T
D
E
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513122
528
59425
F155
R
F
A
E
F
E
D
F
P
E
T
T
E
P
V
Chicken
Gallus gallus
Q5ZIW7
380
43364
N22
L
G
R
Q
H
H
L
N
E
D
K
S
K
L
L
Frog
Xenopus laevis
Q6GPU1
397
45280
L24
E
Y
L
D
L
E
E
L
P
D
S
D
E
P
V
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
T22
E
I
E
D
F
P
E
T
S
D
P
V
W
I
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198708
393
44309
F26
G
M
V
S
F
E
D
F
P
T
D
Q
G
P
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
H22
S
S
S
K
S
D
T
H
D
K
S
P
L
V
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.7
81.5
N.A.
91.9
91.3
N.A.
41.4
78.6
74.3
54.5
N.A.
N.A.
N.A.
N.A.
47.2
Protein Similarity:
100
99.5
99.2
83.9
N.A.
95.7
95.5
N.A.
55.8
86.1
84.9
70.5
N.A.
N.A.
N.A.
N.A.
64.5
P-Site Identity:
100
100
100
80
N.A.
86.6
86.6
N.A.
33.3
13.3
53.3
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
100
N.A.
53.3
26.6
60
33.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
42
17
0
9
17
0
9
75
9
59
0
0
0
% D
% Glu:
17
0
17
9
0
75
67
0
9
9
0
0
67
0
0
% E
% Phe:
50
9
0
0
25
0
0
42
0
0
0
0
0
0
0
% F
% Gly:
9
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% G
% His:
0
0
0
0
9
9
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
9
% I
% Lys:
0
0
0
9
0
0
0
0
0
9
9
0
9
0
0
% K
% Leu:
9
0
9
0
59
0
9
9
0
0
0
0
9
59
17
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
9
0
0
0
9
0
0
75
0
9
9
0
25
0
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% Q
% Arg:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
9
9
9
9
0
0
0
9
0
25
9
0
0
9
% S
% Thr:
0
34
0
0
0
0
9
9
0
9
50
9
0
0
0
% T
% Val:
0
0
9
0
0
0
0
0
0
0
0
9
0
9
67
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
0
9
0
50
0
0
0
25
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _