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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4A
All Species:
44.24
Human Site:
Y266
Identified Species:
88.48
UniProt:
Q8WYN0
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WYN0
NP_443168.2
398
45378
Y266
G
K
P
N
N
A
Y
Y
F
I
G
F
L
G
D
Chimpanzee
Pan troglodytes
XP_529098
398
45427
Y266
G
K
P
N
N
A
Y
Y
F
I
G
F
L
G
D
Rhesus Macaque
Macaca mulatta
XP_001097251
398
45435
Y266
G
K
P
N
N
A
Y
Y
F
I
G
F
L
G
D
Dog
Lupus familis
XP_538136
460
52068
Y328
G
K
P
N
N
A
Y
Y
F
I
G
F
L
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8C9S8
396
45076
Y263
G
K
P
N
N
A
Y
Y
F
I
G
F
L
G
D
Rat
Rattus norvegicus
NP_001119770
406
45887
Y267
G
K
P
N
N
A
Y
Y
F
I
G
S
L
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513122
528
59425
Y400
G
K
P
N
S
A
H
Y
F
I
G
Y
V
G
G
Chicken
Gallus gallus
Q5ZIW7
380
43364
Y249
G
K
P
N
N
A
Y
Y
F
I
G
F
L
G
N
Frog
Xenopus laevis
Q6GPU1
397
45280
Y266
G
K
P
N
H
A
Y
Y
F
I
G
F
S
G
D
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
Y267
G
K
P
N
S
A
H
Y
F
I
G
F
V
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198708
393
44309
Y273
G
K
P
N
H
A
H
Y
F
I
G
V
L
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
G281
G
S
E
D
G
E
R
G
G
A
P
I
L
C
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.7
81.5
N.A.
91.9
91.3
N.A.
41.4
78.6
74.3
54.5
N.A.
N.A.
N.A.
N.A.
47.2
Protein Similarity:
100
99.5
99.2
83.9
N.A.
95.7
95.5
N.A.
55.8
86.1
84.9
70.5
N.A.
N.A.
N.A.
N.A.
64.5
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
66.6
93.3
86.6
80
N.A.
N.A.
N.A.
N.A.
80
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
93.3
100
93.3
100
N.A.
N.A.
N.A.
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
92
0
0
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
75
% D
% Glu:
0
0
9
0
0
9
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
92
0
0
67
0
0
0
% F
% Gly:
100
0
0
0
9
0
0
9
9
0
92
0
0
92
9
% G
% His:
0
0
0
0
17
0
25
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
92
0
9
0
0
9
% I
% Lys:
0
92
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
75
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
92
59
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
0
92
0
0
0
0
0
0
0
9
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% R
% Ser:
0
9
0
0
17
0
0
0
0
0
0
9
9
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
9
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
67
92
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _