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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGCR8
All Species:
6.36
Human Site:
S383
Identified Species:
14
UniProt:
Q8WYQ5
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WYQ5
NP_073557.3
773
86045
S383
V
S
P
V
K
P
L
S
R
S
A
E
L
E
F
Chimpanzee
Pan troglodytes
XP_001167234
783
87207
S383
V
S
P
V
K
P
L
S
R
S
A
E
L
E
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543542
782
86277
S383
P
D
S
I
G
A
D
S
G
A
L
D
E
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQM6
773
86303
G383
V
S
P
V
K
P
L
G
R
S
A
E
L
D
F
Rat
Rattus norvegicus
NP_001099335
773
86341
G383
V
S
P
V
K
P
L
G
R
S
A
E
L
D
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415079
775
87378
D385
V
S
P
I
K
H
I
D
K
S
S
E
L
D
C
Frog
Xenopus laevis
NP_001085043
772
87175
S385
S
V
S
S
S
T
K
S
S
D
T
S
H
N
S
Zebra Danio
Brachydanio rerio
NP_001116221
782
87963
E374
I
S
P
V
K
S
G
E
E
G
I
S
L
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651879
642
71994
Q282
V
T
V
N
E
N
T
Q
K
E
S
I
T
P
E
Honey Bee
Apis mellifera
XP_397444
627
71159
D267
N
R
A
A
H
S
L
D
S
E
Q
L
R
N
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203807
417
47373
P57
N
G
N
L
P
D
Q
P
S
P
A
A
G
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
N.A.
86.4
N.A.
95.3
94.5
N.A.
N.A.
84.3
76
71.7
N.A.
34.1
33.7
N.A.
24
Protein Similarity:
100
98.4
N.A.
89.3
N.A.
96.7
96.1
N.A.
N.A.
90.7
85.6
81.1
N.A.
48.1
50
N.A.
35.5
P-Site Identity:
100
100
N.A.
6.6
N.A.
86.6
86.6
N.A.
N.A.
46.6
6.6
40
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
100
N.A.
33.3
N.A.
93.3
93.3
N.A.
N.A.
80
6.6
46.6
N.A.
33.3
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
10
0
0
0
10
46
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
10
0
0
0
10
10
19
0
10
0
10
0
28
10
% D
% Glu:
0
0
0
0
10
0
0
10
10
19
0
46
10
28
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
37
% F
% Gly:
0
10
0
0
10
0
10
19
10
10
0
0
10
10
0
% G
% His:
0
0
0
0
10
10
0
0
0
0
0
0
10
0
0
% H
% Ile:
10
0
0
19
0
0
10
0
0
0
10
10
0
0
0
% I
% Lys:
0
0
0
0
55
0
10
0
19
0
0
0
0
10
0
% K
% Leu:
0
0
0
10
0
0
46
0
0
0
10
10
55
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
19
0
10
10
0
10
0
0
0
0
0
0
0
19
0
% N
% Pro:
10
0
55
0
10
37
0
10
0
10
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
10
10
0
0
10
0
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
37
0
0
0
10
0
10
% R
% Ser:
10
55
19
10
10
19
0
37
28
46
19
19
0
0
10
% S
% Thr:
0
10
0
0
0
10
10
0
0
0
10
0
10
0
0
% T
% Val:
55
10
10
46
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _