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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DGCR8 All Species: 23.64
Human Site: S613 Identified Species: 52
UniProt: Q8WYQ5 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WYQ5 NP_073557.3 773 86045 S613 S R V Y E L T S K A G L L S P
Chimpanzee Pan troglodytes XP_001167234 783 87207 S613 S R V Y E L T S K A G L L S P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_543542 782 86277 S594 S R V Y E L T S K A G L L S P
Cat Felis silvestris
Mouse Mus musculus Q9EQM6 773 86303 S613 S R V Y E L T S K A G L L S P
Rat Rattus norvegicus NP_001099335 773 86341 S613 S R V Y E L T S K A G L L S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_415079 775 87378 S615 S R V Y E L T S K A G L L S P
Frog Xenopus laevis NP_001085043 772 87175 N612 S R V Y E L T N K A G L L S P
Zebra Danio Brachydanio rerio NP_001116221 782 87963 N622 S R V Y E L T N K A G L L S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651879 642 71994 N487 K T T E P S P N A I L L T C L
Honey Bee Apis mellifera XP_397444 627 71159 S472 C A K T T E P S P H A I L I T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203807 417 47373 I262 E Y F D H V S I D D I R I Y D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98 N.A. 86.4 N.A. 95.3 94.5 N.A. N.A. 84.3 76 71.7 N.A. 34.1 33.7 N.A. 24
Protein Similarity: 100 98.4 N.A. 89.3 N.A. 96.7 96.1 N.A. N.A. 90.7 85.6 81.1 N.A. 48.1 50 N.A. 35.5
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 100 93.3 93.3 N.A. 6.6 13.3 N.A. 0
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 13.3 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 0 0 10 73 10 0 0 0 0 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 0 0 10 0 0 0 0 10 10 0 0 0 0 10 % D
% Glu: 10 0 0 10 73 10 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 73 0 0 0 0 % G
% His: 0 0 0 0 10 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 10 0 10 10 10 10 10 0 % I
% Lys: 10 0 10 0 0 0 0 0 73 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 73 0 0 0 0 10 82 82 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 28 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 10 0 19 0 10 0 0 0 0 0 73 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 73 0 0 0 0 0 0 0 0 0 10 0 0 0 % R
% Ser: 73 0 0 0 0 10 10 64 0 0 0 0 0 73 0 % S
% Thr: 0 10 10 10 10 0 73 0 0 0 0 0 10 0 10 % T
% Val: 0 0 73 0 0 10 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 73 0 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _