KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGCR8
All Species:
22.73
Human Site:
Y721
Identified Species:
50
UniProt:
Q8WYQ5
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WYQ5
NP_073557.3
773
86045
Y721
S
V
I
E
L
Q
Q
Y
A
K
K
N
K
P
N
Chimpanzee
Pan troglodytes
XP_001167234
783
87207
Y721
S
V
I
E
L
Q
Q
Y
A
K
K
N
K
P
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543542
782
86277
L702
A
E
A
V
L
W
S
L
H
P
E
C
P
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQM6
773
86303
Y721
S
V
I
E
L
Q
Q
Y
A
K
K
N
R
P
N
Rat
Rattus norvegicus
NP_001099335
773
86341
Y721
S
V
I
E
L
Q
Q
Y
A
K
K
N
R
P
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415079
775
87378
Y723
S
V
I
E
L
Q
Q
Y
A
K
K
N
K
P
N
Frog
Xenopus laevis
NP_001085043
772
87175
F720
S
V
I
E
L
Q
Q
F
A
K
K
N
K
P
N
Zebra Danio
Brachydanio rerio
NP_001116221
782
87963
Y730
S
V
I
E
L
Q
Q
Y
A
K
K
N
K
P
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651879
642
71994
Q592
Q
S
K
A
A
V
N
Q
P
N
Y
A
I
L
D
Honey Bee
Apis mellifera
XP_397444
627
71159
A577
T
L
L
Q
G
K
A
A
V
N
Q
P
N
H
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203807
417
47373
R367
T
H
D
T
P
R
A
R
P
N
R
K
I
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
N.A.
86.4
N.A.
95.3
94.5
N.A.
N.A.
84.3
76
71.7
N.A.
34.1
33.7
N.A.
24
Protein Similarity:
100
98.4
N.A.
89.3
N.A.
96.7
96.1
N.A.
N.A.
90.7
85.6
81.1
N.A.
48.1
50
N.A.
35.5
P-Site Identity:
100
100
N.A.
6.6
N.A.
93.3
93.3
N.A.
N.A.
100
93.3
100
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
100
N.A.
20
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
6.6
40
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
10
10
0
19
10
64
0
0
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
10
0
64
0
0
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
10
0
0
0
0
10
0
% H
% Ile:
0
0
64
0
0
0
0
0
0
0
0
0
19
0
0
% I
% Lys:
0
0
10
0
0
10
0
0
0
64
64
10
46
0
0
% K
% Leu:
0
10
10
0
73
0
0
10
0
0
0
0
0
19
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
28
0
64
10
0
73
% N
% Pro:
0
0
0
0
10
0
0
0
19
10
0
10
10
64
10
% P
% Gln:
10
0
0
10
0
64
64
10
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
10
0
0
10
0
19
0
0
% R
% Ser:
64
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% S
% Thr:
19
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
64
0
10
0
10
0
0
10
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
55
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _