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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIK3R5 All Species: 26.06
Human Site: S155 Identified Species: 71.67
UniProt: Q8WYR1 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WYR1 NP_001136105.1 880 97348 S155 E Q G L P I R S H R S S T V T
Chimpanzee Pan troglodytes XP_001165830 880 97328 S155 E Q G L P I R S H R S S T V T
Rhesus Macaque Macaca mulatta XP_001118227 885 97661 S159 E Q G L P I R S H R S S T V T
Dog Lupus familis XP_850196 874 96541 S155 E Q G L P I R S H R S S T V T
Cat Felis silvestris
Mouse Mus musculus Q5SW28 871 96935 S155 E Q G L P V R S H R S S T V T
Rat Rattus norvegicus XP_573118 872 96702 S155 E Q G L P I R S H R S S T V T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514581 274 30179
Chicken Gallus gallus Q5ZIB8 881 98356 N153 E Q G L P V K N Y Q S S T V T
Frog Xenopus laevis Q6INI0 879 98911 S154 E Q G I P T R S S C S S T A T
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 92.9 90.9 N.A. 85.8 86.2 N.A. 23.9 61 52.8 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.7 94.1 93.3 N.A. 90 89.6 N.A. 26.9 72.1 66.9 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 100 N.A. 0 66.6 66.6 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 0 100 73.3 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 89 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 89 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 67 0 0 0 0 0 0 % H
% Ile: 0 0 0 12 0 56 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 78 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 89 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 89 0 0 0 0 0 0 0 12 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 78 0 0 67 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 78 12 0 89 89 0 0 0 % S
% Thr: 0 0 0 0 0 12 0 0 0 0 0 0 89 0 89 % T
% Val: 0 0 0 0 0 23 0 0 0 0 0 0 0 78 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _