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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIK3R5
All Species:
20.3
Human Site:
S357
Identified Species:
55.83
UniProt:
Q8WYR1
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WYR1
NP_001136105.1
880
97348
S357
S
S
L
A
S
H
D
S
T
L
S
L
A
S
S
Chimpanzee
Pan troglodytes
XP_001165830
880
97328
S357
S
S
L
A
S
H
D
S
T
L
S
L
A
S
S
Rhesus Macaque
Macaca mulatta
XP_001118227
885
97661
S362
S
S
L
A
S
H
D
S
T
L
S
L
T
S
S
Dog
Lupus familis
XP_850196
874
96541
S357
G
S
A
V
F
H
D
S
T
L
S
L
S
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q5SW28
871
96935
S351
S
S
L
V
S
H
D
S
T
L
L
L
T
S
S
Rat
Rattus norvegicus
XP_573118
872
96702
S351
G
S
L
V
S
H
D
S
E
L
L
L
T
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514581
274
30179
Chicken
Gallus gallus
Q5ZIB8
881
98356
S351
I
S
S
I
S
K
D
S
V
Y
S
A
L
S
E
Frog
Xenopus laevis
Q6INI0
879
98911
F357
N
S
Y
V
Y
W
N
F
P
S
D
S
K
E
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
92.9
90.9
N.A.
85.8
86.2
N.A.
23.9
61
52.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
94.1
93.3
N.A.
90
89.6
N.A.
26.9
72.1
66.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
60
N.A.
80
66.6
N.A.
0
40
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
66.6
N.A.
80
66.6
N.A.
0
40
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
34
0
0
0
0
0
0
0
12
23
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
78
0
0
0
12
0
0
0
12
% D
% Glu:
0
0
0
0
0
0
0
0
12
0
0
0
0
12
12
% E
% Phe:
0
0
0
0
12
0
0
12
0
0
0
0
0
0
0
% F
% Gly:
23
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
67
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
12
0
0
0
0
0
0
12
0
0
% K
% Leu:
0
0
56
0
0
0
0
0
0
67
23
67
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
12
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
45
89
12
0
67
0
0
78
0
12
56
12
12
78
56
% S
% Thr:
0
0
0
0
0
0
0
0
56
0
0
0
34
0
0
% T
% Val:
0
0
0
45
0
0
0
0
12
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
0
12
0
0
0
0
12
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _