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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RSPH1
All Species:
6.06
Human Site:
T149
Identified Species:
11.11
UniProt:
Q8WYR4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WYR4
NP_543136.1
309
35124
T149
V
N
G
Q
Q
E
G
T
A
E
L
I
H
L
N
Chimpanzee
Pan troglodytes
XP_531574
309
35105
T149
V
N
G
Q
Q
E
G
T
A
E
L
I
H
L
N
Rhesus Macaque
Macaca mulatta
XP_001105425
309
35135
A149
V
N
G
Q
Q
E
G
A
A
E
L
I
H
L
N
Dog
Lupus familis
XP_535597
322
36300
A157
V
N
G
Q
Q
E
G
A
A
E
L
I
H
L
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8VIG3
301
34163
A149
V
H
G
Q
Q
E
G
A
A
E
L
I
H
L
N
Rat
Rattus norvegicus
Q641X6
483
53170
G191
N
D
V
F
S
G
L
G
S
L
V
H
C
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511551
370
41653
A208
L
S
G
Q
Q
D
G
A
A
E
L
I
H
L
N
Chicken
Gallus gallus
XP_416745
338
37606
E149
V
N
G
I
Q
E
G
E
A
E
L
I
H
L
N
Frog
Xenopus laevis
Q5PPV3
238
27523
D98
Y
S
G
Y
W
D
N
D
K
K
H
G
Y
G
T
Zebra Danio
Brachydanio rerio
XP_001343012
232
26200
T92
D
G
S
K
Y
E
G
T
W
V
D
D
Q
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609609
344
38803
S156
R
M
K
A
T
W
N
S
N
M
R
T
G
P
F
Honey Bee
Apis mellifera
XP_001122531
424
48545
P251
I
K
D
R
M
Q
G
P
G
Q
L
I
H
P
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790120
287
30719
Q147
I
G
C
E
Q
H
G
Q
Y
V
P
V
E
Q
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
93.1
70.8
N.A.
77.6
21.1
N.A.
49.7
52.9
22.3
48.8
N.A.
32.2
32.5
N.A.
44.9
Protein Similarity:
100
99
96.1
82.9
N.A.
85.1
33.3
N.A.
62.1
65.3
38.5
58.2
N.A.
48.8
43.4
N.A.
56.9
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
0
N.A.
73.3
86.6
6.6
20
N.A.
0
26.6
N.A.
13.3
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
20
N.A.
93.3
86.6
33.3
26.6
N.A.
6.6
53.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
31
54
0
0
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
8
8
8
0
0
16
0
8
0
0
8
8
0
0
0
% D
% Glu:
0
0
0
8
0
54
0
8
0
54
0
0
8
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
16
62
0
0
8
77
8
8
0
0
8
8
8
8
% G
% His:
0
8
0
0
0
8
0
0
0
0
8
8
62
0
0
% H
% Ile:
16
0
0
8
0
0
0
0
0
0
0
62
0
0
0
% I
% Lys:
0
8
8
8
0
0
0
0
8
8
0
0
0
0
0
% K
% Leu:
8
0
0
0
0
0
8
0
0
8
62
0
0
54
0
% L
% Met:
0
8
0
0
8
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
8
39
0
0
0
0
16
0
8
0
0
0
0
0
54
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
8
0
0
16
8
% P
% Gln:
0
0
0
47
62
8
0
8
0
8
0
0
8
8
8
% Q
% Arg:
8
0
0
8
0
0
0
0
0
0
8
0
0
8
8
% R
% Ser:
0
16
8
0
8
0
0
8
8
0
0
0
0
8
0
% S
% Thr:
0
0
0
0
8
0
0
24
0
0
0
8
0
0
8
% T
% Val:
47
0
8
0
0
0
0
0
0
16
8
8
0
0
0
% V
% Trp:
0
0
0
0
8
8
0
0
8
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
8
0
0
0
8
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _