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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KLHL6 All Species: 26.06
Human Site: T493 Identified Species: 57.33
UniProt: Q8WZ60 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WZ60 NP_569713.2 621 70359 T493 T Q C Y D P S T N K W S L K A
Chimpanzee Pan troglodytes XP_001134897 621 70398 T493 T Q C Y D P S T N K W S L K A
Rhesus Macaque Macaca mulatta XP_001106193 619 70154 T491 T Q C Y D P S T N K W S L K A
Dog Lupus familis XP_545220 619 70391 T491 T Q C Y D P S T N K W N L K S
Cat Felis silvestris
Mouse Mus musculus Q6V595 619 70172 T491 T Q C Y D P S T N K W V L K S
Rat Rattus norvegicus Q56A24 600 68346 T467 G G G P D D N T C S D K V Q S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509167 613 69325 T485 T Q C Y D P S T N K W S L K S
Chicken Gallus gallus NP_001026474 316 35882 F190 Q N Y I I Q N F T Q V L S Y E
Frog Xenopus laevis Q6NRH0 564 63190 S438 D G L N I L S S V E R Y D P H
Zebra Danio Brachydanio rerio Q5U374 564 62914 S438 D G L N I L N S V E R Y D P H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUU5 623 68905 N489 E R Y D P R H N K W V A V S P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 98.8 97 N.A. 94.3 44.1 N.A. 82.2 40.2 29.7 29.4 N.A. 31.2 N.A. N.A. N.A.
Protein Similarity: 100 99.8 99.3 98.8 N.A. 96.7 58.9 N.A. 88.8 45.4 46.3 45.8 N.A. 49.1 N.A. N.A. N.A.
P-Site Identity: 100 100 100 86.6 N.A. 86.6 13.3 N.A. 93.3 0 6.6 0 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 40 N.A. 100 13.3 20 20 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 28 % A
% Cys: 0 0 55 0 0 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 19 0 0 10 64 10 0 0 0 0 10 0 19 0 0 % D
% Glu: 10 0 0 0 0 0 0 0 0 19 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 10 28 10 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 19 % H
% Ile: 0 0 0 10 28 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 10 55 0 10 0 55 0 % K
% Leu: 0 0 19 0 0 19 0 0 0 0 0 10 55 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 19 0 0 28 10 55 0 0 10 0 0 0 % N
% Pro: 0 0 0 10 10 55 0 0 0 0 0 0 0 19 10 % P
% Gln: 10 55 0 0 0 10 0 0 0 10 0 0 0 10 0 % Q
% Arg: 0 10 0 0 0 10 0 0 0 0 19 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 64 19 0 10 0 37 10 10 37 % S
% Thr: 55 0 0 0 0 0 0 64 10 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 19 0 19 10 19 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 55 0 0 0 0 % W
% Tyr: 0 0 19 55 0 0 0 0 0 0 0 19 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _